MedTrace Logo

Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation

NCT02321124 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2018-10-09

No results posted yet for this study

Summary

Connective tissue manipulation (CTM) is a manual reflex therapy, which increases intestinal motility by stimulating autonomic nervous system to re-balance the parasympathetic and sympathetic functions. However, there is no randomized controlled trial (RCT) regarding the efficacy of CTM on constipation. This study was planned to investigate the effects of CTM in patients with chronic constipation.

Patients who have diagnosis of chronic constipation according to Rome III criteria were recruited and randomized to intervention and control group. The intervention group received CTM in addition to the lifestyle advice, while the control group was given only lifestyle advice for constipation. All assessments were performed at baseline and at the end of 4 weeks. The primary outcome measure was the Constipation Severity Instrument (CSI). Secondary outcomes included Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL), Bristol Stool Scale (BSS) and 7-day bowel diary. Differences between groups were analyzed with t-tests, Mann-Whitney U test and Chi-square test.

Conditions

  • Chronic Constipation

Interventions

OTHER

connective tissue manipulation

We will apply connective tissue manipulation 5 days a week for four weeks.

BEHAVIORAL

life style advice

We will apply life style advice for four weeks.

Sponsors & Collaborators

  • Hacettepe University

    lead OTHER

Principal Investigators

  • Ceren Gursen · Hacettepe University

  • Mintaze Kerem Gunel · Hacettepe University

  • Serap Kaya · Hacettepe University

  • Taylan Kav · Hacettepe University

  • Türkan Akbayrak · Hacettepe University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2015-07-31
Completion
2015-07-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02321124 on ClinicalTrials.gov