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Hashimoto - a Surgical Disease. Total Thyroidectomy Makes Antibodies Disappear and Ameliorates Symptoms

NCT02319538 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2018-01-17

No results posted yet for this study

Summary

The investigators have already proven that absolute total thyroidectomy gives elimination of anti-TPO antibodies. Our hypothesis is that this elimination also eliminates the typical Hashimoto symptoms, namely: Serious tiredness, increased need of sleep, pain in musculature and joints and dryness in eyes and mouth. The prerequisite for this effect is that the total thyroidectomy is meticulously performed. There exists no other treatment that can eliminate the antibodies. The study is randomized between operation and ordinary conservative medical treatment with thyroxine control and supplementation. The symptoms in both groups are evaluated by 5 different Quality of Life schemes, internationally approved.

Conditions

  • Hashimoto's Disease

Interventions

PROCEDURE

Total thyroidectomy performed

Surgery combined with standard thyroxine treatment

Sponsors & Collaborators

  • Helse Stavanger HF

    collaborator OTHER_GOV

  • Haukeland University Hospital

    collaborator OTHER

  • Sykehuset Telemark

    lead OTHER_GOV

Principal Investigators

  • Ivar Guldvog, MD, PhD · Sykehuset Telemark

  • Hege Kersten, PhD · Sykehuset Telemark

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-02-13
Primary Completion
2017-07-15
Completion
2017-07-15

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02319538 on ClinicalTrials.gov