Bendamustine Hydrochloride in Treating Patients With Previously Treated Multiple Myeloma
NCT02315157 · Status: WITHDRAWN · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2025-10-15
Summary
This phase I trial studies the side effects and best dose of bendamustine hydrochloride in treating patients with previously treated multiple myeloma. Drugs used in chemotherapy, such as bendamustine hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Conditions
- Multiple Myeloma
- Plasma Cell Leukemia
Interventions
- DRUG
-
Given IV
Sponsors & Collaborators
-
Sidney Kimmel Cancer Center at Thomas Jefferson University
lead OTHER
Principal Investigators
-
Manish Sharma, MD · Thomas Jefferson University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-06-30
- Primary Completion
- 2018-11-30
- Completion
- 2018-11-30
Countries
- United States
Study Locations
More Related Trials
-
Carfilzomib, Bendamustine Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT02095834 ·Status: COMPLETED ·Phase: PHASE1
-
Bendamustine, Wkly Bortezomib, Lenalidomide and Dexamethasone for Multiple Myeloma
NCT01484626 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of Bendamustine and IXAZOMIB (MLN9708) Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma
NCT02477215 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study to Evaluate the Combination of Bendamustine, Bortezomib and Dexamethasone (BBD) in the First-Line Treatment of Patients With Multiple Myeloma Who Are Not Candidates for High Dose Chemotherapy
NCT01056276 ·Status: COMPLETED ·Phase: PHASE2
-
Pegylated Liposomal Doxorubicin Hydrochloride, Bortezomib, Cyclophosphamide, and Dexamethasone in Treating Patients With Multiple Myeloma
NCT00849251 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Bendamustine in Combination With Bortezomib and Pegylated Liposomal Doxorubicin for Multiple Myeloma
NCT01177683 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Pilot Study of Bortezomib, Bendamustine and Rituximab on Non-Hodgkin's Lymphoma
NCT00547534 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial Designed to Determine Efficacy and Safety of Bendamustine+Dexamethasone+Thalidomide in R/R MM
NCT01526694 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Bendamustine, Velcade and Dexamethasone in the Treatment of Elderly Patients With Multiple Myeloma
NCT01045681 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Bendamustine Combined With Bortezomib for Patients With Relapsed/Refractory Multiple Myeloma
NCT00920855 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Carfilzomib With Bendamustine and Dexamethasone in Multiple Myeloma
NCT02002598 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Phase II Study of Simvastatin for Relapsed/Refractory Myeloma
NCT01332617 ·Status: WITHDRAWN ·Phase: PHASE2
-
Bendamustine Plus Bortezomib Plus Dexamethasone in Relapsed or Refractory Multiple Myeloma
NCT01168804 ·Status: COMPLETED ·Phase: PHASE2
-
Bendamustine in Combination With Lenalidomide and Dexamethasone in Refractory or Relapsed Multiple Myeloma
NCT01042704 ·Status: COMPLETED ·Phase: PHASE1
-
Bendamustine Bridge to Autologous or Allogeneic Transplant for Relapsed/Refractory Lymphoma
NCT02059239 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Bendamustine, Lenalidomide (Revlimid®) and Dexamethasone (BRd) as 2nd-line Therapy for Patients With Relapsed or Refractory Multiple Myeloma
NCT01701076 ·Status: COMPLETED ·Phase: PHASE2
-
Bendamustine and Melphalan in Myeloma
NCT03187223 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies
NCT02419755 ·Status: TERMINATED ·Phase: PHASE2
-
Isatuximab, Bendamustine, and Prednisone in Refractory Multiple Myeloma
NCT04083898 ·Status: TERMINATED ·Phase: PHASE1
-
Lenalidomide and Pidilizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT02077959 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of PET/CT Scans With the Radioactive Tracer 89Zr-DFO-Daratumumab in People With Myeloma
NCT04467281 ·Status: WITHDRAWN ·Phase: PHASE2
-
Tipifarnib and Bortezomib in Treating Patients With Relapsed Multiple Myeloma
NCT00243035 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT00124579 ·Status: TERMINATED ·Phase: PHASE2
-
Daratumumab, Bortezomib, and Dexamethasone With or Without Venetoclax in Treating Patients With Relapsed or Refractory Multiple Myeloma
NCT03701321 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Bortezomib, Dexamethasone, and Cyclophosphamide in Treating Older Patients With Multiple Myeloma
NCT02082405 ·Status: WITHDRAWN ·Phase: PHASE2