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Well Being And Resilience: Mechanisms of Transmission of Health and Risk

NCT02306551 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 93

Last updated 2023-01-25

No results posted yet for this study

Summary

The purpose of this study is to establish a cohort of pregnant women with severe mental disorder and to identify biological and psycho-social transmission mechanisms involved in the development of 'risk' and 'resilience' in the offspring. It is assumed that both 'resilient' and 'risk' development in offspring are caused by a complex interaction between multiple biological, psychological and social factors. The project focuses specifically on exploring the impact of physiological stress-sensitivity, attachment, care-giving and the familial and social context for care-giving. Previous studies support these factors as important for the development of these infants, but systematic research using a prospective design is needed to strengthen evidence and elucidate the importance of these factors in more detail. The interaction over time of physiological stress-sensitivity, attachment, care-giving and the familial and social context for care-giving are evaluated in terms of the evolution of very early indicators of developmental risk and resilience in infants with a known highly increased risk for developing a mental disorder.The findings of the study may potentially lead to more specific targets for preventive interventions, which can improve developmental outcome for these infants.

Conditions

Interventions

OTHER

Biological and psycho-social risk and resilience factors

Naturalistic study, no active intervention or exposure is administered

Sponsors & Collaborators

  • University of Glasgow

    collaborator OTHER

  • Psychiatric Research Unit, Psychiatry, Region Zealand, Denmark

    collaborator UNKNOWN

  • Region of Southern Denmark

    collaborator OTHER

  • Susanne Harder

    lead OTHER

Principal Investigators

  • Susanne Harder, PhD · Department of Psychology, University of Copenhagen, Denmark

  • Andrew Gumley, PhD · University of Glasgow

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-30
Primary Completion
2020-08-31
Completion
2021-09-30

Countries

  • Denmark
  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02306551 on ClinicalTrials.gov