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Effects of Long Term Antibiotic Therapy on Exacerbation Rate in Stable COPD Patients

NCT02305940 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 222

Last updated 2017-07-26

No results posted yet for this study

Summary

This study investigates if long term use of the antibiotic doxycycline can reduce exacerbations in COPD patients. Half of the patients will receive doxycycline which the other half will receive a placebo.

Conditions

  • Chronic Obstructive Pulmonary Disease (COPD)

Interventions

DRUG

Doxycycline

An oral dose of 100 mg of Doxycycline once daily, for a total duration of 52 weeks.

DRUG

Placebo

An oral dose of one capsule of placebo once daily, for a total duration of 52 weeks

Sponsors & Collaborators

  • Imperial College London

    lead OTHER

Principal Investigators

  • Wisia Wedzicha, MD · Imperial College London

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-07-31
Primary Completion
2017-07-12
Completion
2017-07-12

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02305940 on ClinicalTrials.gov