Randomized Boost Versus no Boost Irradiation of Early Breast Cancer
NCT02295033 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL
Last updated 2014-11-19
Summary
Radiation therapy may kill any tumor cells remaining after surgery. This randomized phase III trial is studying the effect of an extra dose of radiation therapy (Boost dose) after breast conserving surgery and 50 Gy adjuvant external beam radiotherapy to see how well it works compared to no further therapy in treating women with early breast cancer that has been surgically removed.
Conditions
Interventions
- RADIATION
-
Boost irradiation
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Study Design
- Purpose
- TREATMENT
Eligibility
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1989-05-31
- Primary Completion
- 2006-05-31
More Related Trials
-
Hypofractionated Radiation Therapy With Concomitant Boost in Treating Women After Breast Conserving Surgery
NCT03320421 ·Status: COMPLETED ·Phase: NA
-
Accelerated Hypofractionated Whole Breast Irradiation Plus Sequential Boost Versus Concomitant Boost Following BCS
NCT03710733 ·Status: UNKNOWN ·Phase: NA
-
Radiation Therapy After Surgery in Treating Women With Early Stage Breast Cancer
NCT00005587 ·Status: COMPLETED ·Phase: PHASE3
-
Adjuvant Whole Breast Radiotherapy (RT) With Intensity Modulated Radiotherapy (IMRT) and a Simultaneous Integrated Boost Versus Conventional RT and a Sequential Boost
NCT01322854 ·Status: UNKNOWN ·Phase: PHASE3
-
Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction
NCT02927912 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Radiation Dose Intensity Study in Breast Cancer in Young Women
NCT00212121 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Accelerated Partial Breast Irradiation With 3D-CRT and IMRT
NCT02003560 ·Status: UNKNOWN ·Phase: PHASE2
-
Pre- Versus Postoperative Accelerated Partial Breast Irradiation
NCT02913729 ·Status: TERMINATED ·Phase: NA
-
Evaluation of Two Boost Radiation Schedules in Post Lumpectomy Early Stage Carcinoma Breast
NCT02142907 ·Status: COMPLETED
-
IORT-Boost-Study, Prospective Observational Study for Intraoperative Radiotherapy of the Breast as a Boost
NCT02114086 ·Status: UNKNOWN
-
Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer Patients
NCT05762900 ·Status: RECRUITING ·Phase: PHASE2
-
Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery
NCT03324802 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ or Invasive Breast Cancer
NCT00054301 ·Status: COMPLETED ·Phase: PHASE2
-
Postoperative Radiation of Patients With Breast Cancer in Extreme Hypofractionation.
NCT05452083 ·Status: NOT_YET_RECRUITING
-
Radiation Therapy in Treating Women Who Have Undergone Surgery for Early-Stage Invasive Breast Cancer
NCT00005957 ·Status: COMPLETED ·Phase: NA
-
Concurrent Boost Radiotherapy
NCT00981864 ·Status: COMPLETED ·Phase: PHASE2
-
Whole Breast Irradiation vs Twice Daily vs. Once Daily Accelerated Partial Breast Irradiation
NCT03616626 ·Status: UNKNOWN ·Phase: NA
-
Partial Breast Radiation Therapy in Treating Women Undergoing Breast-Conserving Therapy for Early Stage Breast Cancer
NCT00527293 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
NCT00103181 ·Status: COMPLETED ·Phase: NA
-
Safety Study of the Hypo-fractionated (Large Doses) Radiation Therapy in Post-menopausal Women With Breast Cancers
NCT02883985 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast Cancer
NCT00599989 ·Status: COMPLETED ·Phase: NA
-
Intraoperative Electron Radiotherapy for Low-risk Early Breast Cancer
NCT03838419 ·Status: SUSPENDED ·Phase: NA
-
Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer
NCT03359954 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Intraoperative Radiotherapy for Korean Patients With Breast Cancer
NCT02213991 ·Status: UNKNOWN ·Phase: PHASE2
-
APBI Versus EBRT Therapy After Breast Conserving Surgery for Low-risk Breast Cancer
NCT00402519 ·Status: UNKNOWN ·Phase: PHASE3