ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell Tumors
NCT02290132 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 63
Last updated 2014-11-13
Summary
The clinical application and effect of ATG based myeloablative conditioning regimen after allogeneic hematopoietic stem cell transplantation in adult patients with aggressive T-cell lymphomas.
Conditions
- Acute Lymphoblastic Leukemia
- Lymphoblastic Lymphoma
Interventions
- DRUG
-
Rabbit Anti-human Thymocyte Globulin (ATG)
The conditioning regimen in this study consisted of Rabbit antithymocyte globulin (ATG 2.5 mg/kg×4 days) , total-body irradiation (10 Gy in five fractions), cyclophosphamide (60 mg/kg×2 days) and etoposide or teniposide (30-40mg/kg) .
Sponsors & Collaborators
-
Tang-Du Hospital
collaborator OTHER -
The First Affiliated Hospital of Soochow University
collaborator OTHER -
The First Affiliated Hospital with Nanjing Medical University
collaborator OTHER -
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
liu guohua, doctor · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-08-31
- Primary Completion
- 2016-12-31
- Completion
- 2017-07-31
Countries
- China
Study Locations
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