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Pharmacokinetics of Prednisone in Adults

NCT02274402 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 114

Last updated 2025-11-20

No results posted yet for this study

Summary

This is a monocentric study, in the Internal Medicine Service of Cochin Hospital, Paris. Our main objective is to determine the pharmacokinetic properties of prednisone, secondary objectives are to determine the covariates affecting the prednisone pharmacokinetics and the relationship between glucocorticoid exposition levels and their side effects. The investigators will use a prospective, observational, population pharmacokinetic approach. 100 patients starting a prednisone treatment \>7,5mg/d for an expected period \>3 months will be recruited and followed over 6 months.

Conditions

  • Patients Receiving Prednisone

Interventions

BIOLOGICAL

blood sampling

Blood sample of 4 ml at enrolment and then at two following visits

Sponsors & Collaborators

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Jean-Marc Treluyer, M.D., PhD · Assistance Publique - Hôpitaux de Paris

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-11-30
Primary Completion
2015-11-30
Completion
2016-06-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02274402 on ClinicalTrials.gov