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Rational Therapeutics Based on Matched Tumor and Normal Tissue

NCT02272595 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3

Last updated 2022-02-15

No results posted yet for this study

Summary

The goal of this laboratory research study is to learn if using molecular information (matched therapy) or not using molecular information and having the study doctor choose the therapy based on your past experience are more effective ways to choose the best cancer treatment for you.

This is an investigational study.

Up to 200 participants will take part in this study. Up to 50 will be enrolled at MD Anderson.

Conditions

Interventions

OTHER

Treatment Based on Genetic Mutation

Participant's molecular profile shows that they have a gene mutation that may benefit from study drugs that are believed to target their gene mutation. Participant assigned to Arm A and will receive these targeted drugs.

OTHER

Treatment Based on No Genetic Mutation

Participant's molecular profile shows that they do not have a gene mutation. Participant assigned to Arm B in which doctor chooses a therapy based on other studies rather than gene mutation.

Sponsors & Collaborators

Principal Investigators

  • Apostolia M. Tsimberidou, MD, PHD · M.D. Anderson Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-11-04
Primary Completion
2022-01-11
Completion
2022-01-11

Countries

  • United States
  • France
  • Israel
  • Spain

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02272595 on ClinicalTrials.gov