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Impact of Cerebellar Mass Resection on Pain Processing

NCT02261649 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2018-02-01

No results posted yet for this study

Summary

The purpose of the study is to evaluate how cerebellar resection surgery may affect pain sensation and the way the brain "reads" pain signals. By measuring brain activity in children and adolescents following surgery, the investigators hope to gain valuable information about pain processing in the brain.

Conditions

  • Cerebellar Neoplasm

Interventions

DEVICE

Medoc Advanced Medical Systems PATHWAY Model ATS

30 minutes of sensory testing using a contact thermal stimulator will measure thresholds for heat and cool detection, and threshold for hot and cold pain.

PROCEDURE

Cold water bath

The next 15 minutes of sensory testing will measure tolerance to having right or left hand in a tub of cold water. The participant will place their hand in cold water and leave it there for as long they can, even if it is uncomfortable. The participant can take their arm out if it gets too uncomfortable to leave it in.

DEVICE

MRI scanner

An MRI will be used to collect anatomical and functional images from patients and subjects. These data will be collected within a 1 hour block.

OTHER

Questionnaires

The surveys include questions about emotions, thoughts, and feelings. These surveys will be given before sensory testing and before the MRI scan. The parent or guardian will help to complete two surveys, and will complete one survey on his or her own. Questions can be skipped, and may be stopped at any time.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Cancer Institute (NCI)

    collaborator NIH

  • Dana-Farber Cancer Institute

    lead OTHER

Principal Investigators

  • Eric Moulton, Ph.D · Boston Children's Hospital

Eligibility

Min Age
6 Years
Max Age
38 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2017-04-30
Completion
2017-12-31

Countries

  • United States

Study Locations

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Entities

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02261649 on ClinicalTrials.gov