Study to Assess Potential Different Properties of Telmisartan Compared to Candesartan in Healthy Volunteers
NCT02261116 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2014-10-10
Summary
Study to assess potential different properties of telmisartan, which due to its Vd, should result in stronger "beneficial" effects of AT1 blockade in tissues (e.g. aldosterone suppression and renin increase) plus stronger AT2 stimulation compared to candesartan
Conditions
- Healthy
Interventions
- DRUG
-
Telmisartan
- DRUG
-
Candesartan
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2002-04-30
- Primary Completion
- 2002-08-31
More Related Trials
-
Double-Blind Randomized Cross-Over Trial Comparing Metabolic Effects of Candesartan, Hydrochlorothiazide and Placebo
NCT00282178 ·Status: COMPLETED ·Phase: PHASE2
-
Study Describing the Hypertensive Population Treated With Telmisartan and Conditions of Use by Medical Practitioners and Patients
NCT02242851 ·Status: COMPLETED
-
Randomized, Double-Blind, Placebo-Controlled, Forced-Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Weeks in Patients With Stage 1 and Stage 2 Hypertension
NCT00168779 ·Status: COMPLETED ·Phase: PHASE4
-
Candesartan Effect in Second Stage Arterial Hypertension
NCT00621153 ·Status: COMPLETED ·Phase: PHASE4
-
Micardis®. Observational Study in Patients With Essential Hypertension
NCT02200094 ·Status: COMPLETED
-
Safety, Tolerability and Efficacy of Micardis® in Patients With Essential Hypertension
NCT02176850 ·Status: COMPLETED
-
A Randomized, Double-blind, Placebo Controlled Comparison of Telmisartan Hydrochlorothiazide (HCT) and Valsartan HCT in Hypertension (HTN) Stage I/II Patients
NCT00240448 ·Status: COMPLETED ·Phase: PHASE4
-
MICARDIS® and Valsartan in Patients With Mild-to-Moderate Hypertension Using Ambulatory Blood Pressure Monitoring
NCT02177396 ·Status: COMPLETED ·Phase: PHASE3
-
The Clinical Study to Evaluate the Efficacy and Safety of Fimasartan in Patients With Mild to Moderate Essential Hypertension
NCT01135212 ·Status: COMPLETED ·Phase: PHASE3
-
Using Telmisartan Alone or Combination of Telmisartan -HCTZ in the Treatment of Mild to Moderate Essential Hypertension
NCT00638911 ·Status: COMPLETED
-
Study to Evaluate Efficacy of Micardis® (Telmisartan) and Valsartan in Patients With Mild-to-moderate Hypertension After Missing One Dose Using Ambulatory Blood Pressure Monitoring
NCT02242318 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase 2 Dose Selection Trial of Candesartan Cilexetil and Amlodipine Besylate to Treat Essential Hypertension
NCT02059616 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control
NCT02521233 ·Status: WITHDRAWN ·Phase: PHASE3
-
Efficacy and Safety of a Therapy Change From Candesartan 32 mg to Fixed Combination of Olmesartan 40 mg/Amlodipine 10 mg
NCT01611077 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacovigilance and Patient Compliance in Hypertensive Patients
NCT02200575 ·Status: COMPLETED
-
A Study to Evaluate the Efficacy and Safety of Amlodipine Besylate and Candesartan Cilexetil in Essential Hypertension Patient Who Are Not Adequately Controlled With Candesartan Cilexetil Monotherapy
NCT02368652 ·Status: COMPLETED ·Phase: PHASE3
-
Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo
NCT00434967 ·Status: COMPLETED ·Phase: PHASE3
-
Candesartan Effectiveness Study in Pro-B Type Natriuretic Peptides (BNP)
NCT00348686 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Candesartan Cilexetil Plus Hydrochlorothiazide in Subjects With Severe Hypertension
NCT01012479 ·Status: COMPLETED ·Phase: PHASE4
-
Antihypertensive Efficacy and Safety of Candesartan/HCT 32/12.5 and 32/25 mg in Comparison With Candesartan 32 mg
NCT00383929 ·Status: COMPLETED ·Phase: PHASE3
-
1 Year Trial Telmisartan 80 mg Versus Valsartan 160 mg in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy
NCT00153023 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Angiotensin Converting Enzyme (ACE) Inhibitors Versus Candesartan in Reducing Cardiovascular Events in Primary Treatment of Hypertension
NCT01152567 ·Status: COMPLETED
-
A Dose Selection Trial of CKD-330 in Patients With Essential Hypertension
NCT02206165 ·Status: UNKNOWN ·Phase: PHASE2
-
Bioavailability Study of Candesartan Cilexetil 16mg Tablet Under Fasting Conditions
NCT02006602 ·Status: COMPLETED ·Phase: PHASE1
-
Changes After Angiotensin Converting Enzyme (ACE) Inhibitor Replacement by Angiotensin II Receptor Type I (AT1) Blocker
NCT01444833 ·Status: UNKNOWN ·Phase: NA