Trial Outcomes & Findings for Amsterdam Stool Scale: Usefulness in Clinical Setting (NCT NCT02252718)

NCT ID: NCT02252718

Last Updated: 2017-02-23

Results Overview

The outcome measures were interrater variability in the stool assessment by the parent and MD1 made in vivo and in the assessment by the parent in vivo and by MD2 based on the photograph(s). The IV was evaluated by calculating the proportion of exact agreement and the κ statistics for nominal data (colour) and weighted κ values for items in which there is a natural ordering of categories (consistency and amount). Correlation, based on the value of kappa (κ), was categorized as poor (κ ≤ 0.2), fair (0.21 ≤ κ ≤ 0.40), moderate (0.41 ≤ κ ≤ 0.60), good (0.61 ≤ κ ≤ 0.80) or excellent (0.81 ≤ κ ≤ 1.00).

Recruitment status

COMPLETED

Target enrollment

100 participants

Primary outcome timeframe

<5min after defecation

Results posted on

2017-02-23

Participant Flow

This study was conducted at the Department of Paediatrics of the Medical University of Warsaw between September 2014 and February 2015.

Participant milestones

Participant milestones
Measure
Children 2-18 Months of Age
Children aged between 2 and 18 months of age, who were not toilet trained, admitted to the Department of Pediatrics The Medical University of Warsaw Stool Assessment: After passing a stool by the child participating in the study, within the shortest possible time (\<5 min), the stool will be assessed independently and simulataneously by one of the parents and the medical doctor. They were unaware of the evaluation results made by the other. At the same time 2 photos were taken with smartphone camera. Then the photographs were subsequently evaluated by the other physician (MD2), who was unaware of the in vivo stool evaluation.
Overall Study
STARTED
100
Overall Study
COMPLETED
100
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Amsterdam Stool Scale: Usefulness in Clinical Setting

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Children 2-18 Months of Age
n=100 Participants
Children between 2 and 18 months of age who were not toilet trained
Age, Continuous
5.02 month
STANDARD_DEVIATION 4.4 • n=99 Participants
Gender
Female
42 Participants
n=99 Participants
Gender
Male
58 Participants
n=99 Participants

PRIMARY outcome

Timeframe: <5min after defecation

The outcome measures were interrater variability in the stool assessment by the parent and MD1 made in vivo and in the assessment by the parent in vivo and by MD2 based on the photograph(s). The IV was evaluated by calculating the proportion of exact agreement and the κ statistics for nominal data (colour) and weighted κ values for items in which there is a natural ordering of categories (consistency and amount). Correlation, based on the value of kappa (κ), was categorized as poor (κ ≤ 0.2), fair (0.21 ≤ κ ≤ 0.40), moderate (0.41 ≤ κ ≤ 0.60), good (0.61 ≤ κ ≤ 0.80) or excellent (0.81 ≤ κ ≤ 1.00).

Outcome measures

Outcome measures
Measure
Children 2-18 Months of Age
n=100 Participants
Children aged between 2 and 18 months of age, who were not toilet trained, admitted to the Department of Pediatrics The Medical University of Warsaw Stool Assessment: After passing a stool by the child participating in the study, within the shortest possible time (\<5 min), the stool will be assessed independently and simulataneously by one of the parents and the medical doctor. They were unaware of the evaluation results made by the other. At the same time 2 photos were taken with smartphone camera. Then the photographs were subsequently evaluated by the other physician (MD2), who was unaware of the in vivo stool evaluation.
Interrater Variability (IV)
parent- MD1: amount
0.79 kappa value
Interval 0.7 to 0.88
Interrater Variability (IV)
parent- MD1: consistency
0.87 kappa value
Interval 0.78 to 0.95
Interrater Variability (IV)
parent- MD1: color
0.81 kappa value
Interval 0.71 to 0.91
Interrater Variability (IV)
parent- MD2: amount
0.44 kappa value
Interval 0.3 to 0.59
Interrater Variability (IV)
parent- MD2: consistency
0.5 kappa value
Interval 0.36 to 0.64
Interrater Variability (IV)
parent- MD2: color
0.33 kappa value
Interval 0.21 to 0.45

Adverse Events

Children 2-18 Months of Age

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Katarzyna Wojtyniak

Medical University of Warsaw

Phone: (+48) 223179536

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place