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Pharmacokinetics of Glucocorticoids in Children (GLUCOPED)

NCT02252237 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 146

Last updated 2025-11-20

No results posted yet for this study

Summary

The purpose of this study is to determine individual susceptibility factors (drug interactions, genetic factors such as enzyme polymorphism…) to explain wide interindividual variability towards corticosteroids (prednisone, prednisolone, methylprednisolone, hydrocortisone) in children, which could establish a base for therapeutic monitoring.

Conditions

  • Children Receiving Prednisone or Prednisolone or Methylprednisolone or Hydrocortisone

Interventions

BIOLOGICAL

Pharmacokinetic

Blood sample of 2 ml at enrolment and then at following visits. Buccal cell collection swab

Sponsors & Collaborators

  • URC-CIC Paris Descartes Necker Cochin

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Jean-Marc Tréluyer, MD-PhD · Assistance Publique - Hôpitaux de Paris

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-12-03
Primary Completion
2021-12-09
Completion
2021-12-09

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02252237 on ClinicalTrials.gov