Autologous Dendritic Cell Therapy in Patients With Relapsed or Refractory Multiple Myeloma
NCT02248402 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2014-09-25
Summary
Multiple myeloma remains incurable disease in most patients . Cellular immunotherapy using dendritic cells is emerging as a useful immunotherapeutic modality to treat multiple myeloma. Vax-DC/MM is an potent immunotherapeutic agent generated by dendritic cells loaded with the ultraviolet B-irradiated autologous human myeloma cells. The main purpose of this study is to examine the safety and efficacy of Vax-DC/MM in patients with relapsed or refractory multiple myeloma.
Conditions
Interventions
- BIOLOGICAL
-
Vax-DC/MM
Sponsors & Collaborators
-
Chonnam National University Hospital
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-10-31
- Primary Completion
- 2015-10-31
Countries
- South Korea
Study Locations
More Related Trials
-
Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC)
NCT04614051 ·Status: TERMINATED ·Phase: PHASE1
-
Dendritic Cell Vaccination for Patients with Solid Tumors
NCT01291420 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccination for Postremission Therapy in AML
NCT01734304 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase II Feasibility Study of Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme
NCT00323115 ·Status: COMPLETED ·Phase: PHASE2
-
Dendritic Cell Based Therapy of Malignant Melanoma
NCT00197912 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Efficacy of Dendritic Cell Therapy for Myeloid Leukemia and Myeloma
NCT00965224 ·Status: COMPLETED ·Phase: PHASE2
-
Trial of Vaccine Therapy With mRNA- Transfected Dendritic Cells in Patients With Advanced Malignant Melanoma
NCT01278940 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study of ICT-121 Dendritic Cell Vaccine in Recurrent Glioblastoma
NCT02049489 ·Status: COMPLETED ·Phase: PHASE1
-
Dendritic Cell (DC) Activated Cytokine-induced Killer Cell (DCIK) Combined With DC Treatment for Glioma
NCT01235845 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
DC Vaccine Combined With IL-2 and IFNα-2a in Treating Patients With mRCC
NCT00085436 ·Status: COMPLETED ·Phase: PHASE2
-
Dendritic Cell Vaccination in Patients With Advanced Melanoma
NCT03092453 ·Status: COMPLETED ·Phase: PHASE1
-
Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma
NCT00846456 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety Evaluation of Autologous Dendritic Cell Anticancer Immune Cell Therapy (Cellgram-DC-PC)
NCT04615845 ·Status: TERMINATED ·Phase: PHASE1
-
Active Immunotherapy Of Metastatic Renal Cell Carcinoma Using Autologous Dendritic Cells Transfected With Autologous Total Tumor RNA
NCT00006431 ·Status: UNKNOWN ·Phase: PHASE1
-
Autologous Dendritic Cell Vaccination in Mesothelioma
NCT02649829 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma
NCT01875653 ·Status: TERMINATED ·Phase: PHASE3
-
Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor
NCT00377247 ·Status: TERMINATED ·Phase: PHASE1
-
Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in Remission
NCT01686334 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dendritic Cell-based Immunotherapy Combined With Low-dose Cyclophosphamide in Patients With Malignant Mesothelioma
NCT01241682 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccination of Patients With Stage IV Melanoma With Dendritic Cells
NCT00125749 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Autologous Dendritic Cell Vaccine in Kidney Cancer
NCT05127824 ·Status: RECRUITING ·Phase: PHASE2
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating Patients With Renal Cell Carcinoma
NCT00862303 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating
NCT02487550 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Dendritic Cell Vaccination in Melanoma Patients Scheduled for Regional Lymph Node Dissection
NCT00243594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccination in CML
NCT02543749 ·Status: TERMINATED ·Phase: PHASE1/PHASE2