"Preventing Cardiovascular Ischemic Events and Arresting Their Consequences in Type 2 Diabetic Population

Summary

Current methods based on traditional Cardiovascular risk factors are not clinically useful for identifying Type 2 Diabetes patients at risk of developing acute Cardiovascular ischemic events (ie.myocardial infarction or stroke). In addition, Cardiovascular ischemic events in Type 2 Diabetes population have worse prognosis than in general population. In fact, there is sufficient experimental evidence indicating that diabetes exaggerates the deleterious effects of ischemic events and worsens their outcome.

A prolonged sub-clinical phase exists before a Cardiovascular event occurs in Type 2 Diabetes patients. Therefore, new strategies aimed at identifying those patients with this subclinical Cardiovascular Diabetes and, consequently, more prone to develop Cardiovascular events is a challenge to be met.

Conditions

• Type2 Diabetes Mellitus
• Microangiopathy
• Non Alcoholic Fatty Liver Disease
• Coronary Artery Disease
• Cerebrovascular Disease
• Acute Coronary Syndrome/ Myocardial Infarction
• Ictus

Sponsors & Collaborators

• Hospital Universitari Vall d'Hebron Research Institute

  lead OTHER

Principal Investigators

• David García-Dorado Garcia, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Joan Montaner Vilallonga, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Rafael Simó Canonge, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Joan Sayós Ortega, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Daniel Serón Micas, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Joan Genescà Ferrer, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Santiago Aguadé Bruix, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

• Joan Xavier Comella Carnicé, PhD MD · Hospital Universitario Valle de Hebron, Barcelona, Spain

Eligibility

Min Age

50 Years

Max Age

79 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2014-09-30

Primary Completion

2018-02-28

Completion

2018-10-31

Countries

• Spain

Study Locations