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Mifepristone for the Prevention of Relapses of Alcohol Drinking

NCT02243709 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2025-01-10

Study results available
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Summary

The goal of this study is to determine if, under stress, alcohol drinking is reduced using mifepristone

Conditions

  • Alcohol Use Disorders (AUD)

Interventions

DRUG

Mifepristone 600-mg/day or placebo for a week

600-mg of mifepristone for a week, compared to placebo for a week, in a stress-induced condition triggered by a single dose of 32.4 mg of yohimbine

Sponsors & Collaborators

  • Brown University

    lead OTHER

Principal Investigators

  • Carolina L Haass-Koffler, PharmD · Brown University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-30
Primary Completion
2021-12-21
Completion
2021-12-21

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02243709 on ClinicalTrials.gov