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Clomiphene Citrate in Combination With Gonadotropins for Ovarian Stimulation in Women With Poor Ovarian Response.

NCT02237755 · Status: UNKNOWN · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2014-09-11

No results posted yet for this study

Summary

Coadministration of various drugs used for ovarian stimulation can increase the efficiency of IVF especially in poor responders. The investigators hypothesize that ovarian response of those patients could improve by using combination of clomiphene citrate with gonadotropins in infertile women with poor response to gonadotrophin administration only.

Conditions

  • Female Infertility

Interventions

DRUG

Clomiphene citrate

clomiphene citrate 100mg/day will be added to the standard gonadotropin regiment

DRUG

Gonadotropins

All patients will be stimulated with a fixed GnRH-antagonist protocol. Ovarian stimulation will be initiated with 450 IU of gonadotropins either in the form of a combination of highly purified urinary FSH and LH or with a combination of Rec FSH and Rec LH.

Sponsors & Collaborators

  • Lito Maternity Hospital

    collaborator OTHER

  • University of Athens

    lead OTHER

Principal Investigators

  • Nikos Vlahos, Assoc. Prof. · University of Athens, 2nd Department of Obstetrics and Gynecology

  • Olga Triantafyllidou, MD · University of Athens School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2014-11-30
Completion
2015-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02237755 on ClinicalTrials.gov