Prediction of Acute Postoperative Pain and Analgesic Consumption

NCT02230865 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2015-06-01

No results posted yet for this study

Summary

Pain is an expected part of surgical recovery but effective pain management remains challenging. The high variability in postoperative pain experience and analgesic treatment response between patients is part of the challenge. Few studies have yet combined preoperative assessment of responses to experimental pain with measurements of cognitive and emotional processes in the prediction of postoperative pain.

We hypothesize, that preoperative evoked brain potentials (using standard electroencephalographic brain imaging), endogenous pain inhibition capacity (conditioned pain modulation), responses to pressure/thermal pain stimulation, and/or situational pain-related catastrophic thinking are useful clinical predictors of postoperative pain and analgesic consumption.

Conditions

  • Postoperative Pain

Sponsors & Collaborators

  • Kasper Grosen

    lead OTHER

Principal Investigators

  • Asbjørn M Drewes, MD, PhD, DMSci · Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Denmark

  • Kasper Grosen, MHSc, PhD · Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Denmark

  • Hans K Pilegaard, MD · Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Denmark

  • Lene Vase, MSc (Psychology), PhD · Department of Psychology, Aarhus University, Denmark

  • Mogens Pfeiffer-Jensen, MD, PhD · Aarhus University Hospital

  • Vibeke E Hjortdal, MD, PhD, DMSci · Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Denmark

  • Anne E Olesen, PhD · Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Denmark

  • Mikkel Gram, MScEE · Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Denmark

Eligibility

Min Age
15 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2015-06-30
Completion
2015-06-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02230865 on ClinicalTrials.gov