Endothelial Microparticles: A Novel Marker of Vascular Dysfunction
NCT02230202 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2018-02-28
Summary
The primary hypothesis of this proposal is that chronic kidney disease (CKD) and treatment with calcineurin inhibitors (CNIs) are each associated with the release of endothelial microparticles into the plasma.
Conditions
Interventions
- OTHER
-
Flow-mediated dilation
Flow-mediated dilation used to measure vascular function. The test is minimally invasive, with only a slight discomfort due to the inflation of the arm cuff.
- OTHER
-
single blood draw
single blood draw of approximately 45 mL.
Sponsors & Collaborators
-
University of Colorado, Denver
lead OTHER
Principal Investigators
-
Joshua M Thurman, MD · University of Colorado, Denver
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-09-30
- Primary Completion
- 2016-03-31
- Completion
- 2016-03-31
Countries
- United States
Study Locations
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