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Effect of Sodium Bicarbonate Buffered Lidocaine on the Success of IAN Block of Teeth With Irreversible Pulpitis

NCT02226913 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2016-08-31

No results posted yet for this study

Summary

Buffering of local anesthetics (alkalinization) has been suggested in achieving pain control. The purpose of this prospective, randomized, double-blind study was to evaluate the effect of adding 0.6 mL 8.4% sodium bicarbonate to 3.0 mL 2% lidocaine with 1: 80,000 epinephrine on the success rate of IAN block for endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.

Conditions

  • Local Anesthesia

Interventions

DRUG

2% lidocaine with 1:80,000 epinephrine

2% lidocaine with 1:80,000 epinephrine

DRUG

sodium bicarbonate

8.4% sodium bicarbonate

DRUG

placebo

sterile distilled water (Samen Pharmaceutical Co, Iran)

Sponsors & Collaborators

  • Masoud Saatchi

    lead OTHER

Principal Investigators

  • Masoud Saatchi, DDS MSc · Isfahan University of Medical Sciences

Study Design

Allocation
RANDOMIZED
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-02-28
Primary Completion
2013-09-30
Completion
2013-09-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02226913 on ClinicalTrials.gov