Ticagrelor Versus Clopidogrel in Left Ventricular Remodeling After ST-segment Elevation Myocardial Infarction

Summary

The purpose of the study is to evaluate the novel role of ticagrelor to improve long-term LV remodeling following ST-segment elevation myocardial infarction.

Conditions

• ST Elevation Myocardial Infarction

Interventions

DRUG

Ticagrelor

Ticagrelor 180 mg as a loading dose and 90 mg twice daily as a maintenance dose

DRUG

Clopidogrel

Clopidogrel 600 mg as a loading dose and 75 mg once daily as a maintenance dose.

Sponsors & Collaborators

• Chinese PLA General Hospital

  collaborator OTHER

• Chungnam National University Hospital

  collaborator OTHER

• Pusan National University Yangsan Hospital

  collaborator OTHER

• National University Heart Centre, Singapore

  collaborator OTHER

• Ulsan University Hospital

  collaborator OTHER

• Kyungpook National University Hospital

  collaborator OTHER

• Samsung Changwon Hospital

  collaborator OTHER

• Kyunghee University Medical Center

  collaborator OTHER

• Chungbuk National University Hospital

  collaborator OTHER

• Chonnam National University Hospital

  collaborator OTHER

• Seoul National University Bundang Hospital

  collaborator OTHER

• Gyeongsang National University Hospital

  lead OTHER

Principal Investigators

• Yongwhi Park, MD., PhD. · Gyeongsang National University Hospital

• Young-Hoon Jeong, MD.,PhD. · Gyeongsan National University Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2017-06-30

Completion

2017-12-31

Countries

• China
• Singapore
• South Korea

Study Locations