MedTrace Logo

Restoring Glutathione Synthesis With Tecfidera: An in Vivo H-MRS Single-Arm Study at 7T in Patients With RR MS

NCT02218879 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 7

Last updated 2016-09-05

No results posted yet for this study

Summary

The primary objective is to directly estimate brain glutathione concentrations in vivo using H-MRS at 7T before and after initiation of Tecfidera in established multiple sclerosis (MS) patients considering switching therapy or being treatment-naive (first line).

Conditions

Interventions

DRUG

Tecfidera

Oral Tecfidera 240 mg bid

Sponsors & Collaborators

  • Yale University

    lead OTHER

Principal Investigators

  • Daniel Pelletier, MD · Yale University

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2016-04-30
Completion
2016-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02218879 on ClinicalTrials.gov