A Study of MLN0264 in Patients With Pancreatic Cancer
NCT02202785 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 43
Last updated 2017-05-15
Summary
The purpose of this study is to assess the efficacy, safety and tolerability of MLN0264 in patients with advanced or metastatic guanylyl cyclase C (GCC)-positive adenocarcinoma of the pancreas.
Conditions
- Pancreatic Adenocarcinoma
Interventions
- DRUG
-
MLN0264
MLN0264 IV infusion
Sponsors & Collaborators
-
Millennium Pharmaceuticals, Inc.
lead INDUSTRY
Principal Investigators
-
Medical Director Clinical Science · Millennium Pharmaceuticals, Inc.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-07-02
- Primary Completion
- 2016-01-15
- Completion
- 2016-01-15
Countries
- United States
- Belgium
- Spain
- United Kingdom
Study Locations
More Related Trials
-
M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the Pancreas
NCT03451773 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
NCT04665947 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Lenalidomide With Gemcitabine in Treatment of Untreated Advanced Carcinoma of the Pancreas
NCT00837031 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of CP-4126 in Patients With Advanced Pancreatic Cancer
NCT00913198 ·Status: COMPLETED ·Phase: PHASE2
-
Abraxane Therapy in Patients With Pancreatic Cancer Who Failed First-Line Gemcitabine Therapy
NCT00691054 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate Efficacy of CO-1.01 as Second Line Therapy for Gemcitabine-Refractory Stage IV Pancreatic Adenocarcinoma
NCT01233375 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer
NCT02581215 ·Status: COMPLETED ·Phase: PHASE2
-
To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
NCT07303465 ·Status: RECRUITING ·Phase: PHASE2
-
Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma
NCT06861452 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer
NCT01373164 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Pharmacokinetics of SM04755 in Subjects With Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer
NCT02191761 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic Cancer
NCT00245362 ·Status: COMPLETED ·Phase: PHASE2
-
Dolastatin 10 in Treating Patients With Metastatic Pancreatic Cancer
NCT00003677 ·Status: COMPLETED ·Phase: PHASE2
-
BMS-247550 in Treating Patients With Advanced Pancreatic Cancer
NCT00016965 ·Status: COMPLETED ·Phase: PHASE2
-
RNA Precision Oncology in Advanced Pancreatic Cancer
NCT04476537 ·Status: TERMINATED ·Phase: NA
-
ISIS 2503 in Treating Patients With Advanced Cancer of the Pancreas
NCT00005594 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer
NCT02570711 ·Status: TERMINATED ·Phase: PHASE2
-
Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer
NCT04887805 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic Cancer
NCT00652054 ·Status: COMPLETED ·Phase: PHASE2
-
Olaparib in Treating Patients With Stage IV Pancreatic Cancer
NCT02677038 ·Status: COMPLETED ·Phase: PHASE2
-
An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid Tumors
NCT01822756 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase I/II Study of Lenalidomide in Combination With Gemcitabine in Patients With Untreated Advanced Carcinoma of the Pancreas
NCT00179751 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Lenalidomide and Gemcitabine as First-line Treatment in Patients With Pancreatic Cancer
NCT01547260 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancer
NCT01232829 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study of MEDI4736 Monotherapy or in Combinations With Tremelimumab in Metastatic Pancreatic Ductal Carcinoma
NCT02558894 ·Status: COMPLETED ·Phase: PHASE2