Residual Renal Function Preservation in Peritoneal Dialysis Patients
NCT02190318 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96
Last updated 2014-08-01
Summary
Aldosterone blockade is useful in preserving residual renal function in patients on PD.The long term efficacy of dual blockade of the RAAS is better than monotherapy.
Conditions
- Chronic Renal Disease
Interventions
- DRUG
-
Losartan
- DRUG
-
spirolactone
- OTHER
-
blank control
Sponsors & Collaborators
-
Baxter Healthcare Corporation
collaborator INDUSTRY -
Second Xiangya Hospital of Central South University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-11-30
- Primary Completion
- 2015-12-31
- Completion
- 2015-12-31
Countries
- China
Study Locations
More Related Trials
-
Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency
NCT00338091 ·Status: TERMINATED ·Phase: NA
-
Effects of Angiotensin Receptor Antagonist on Prohibiting Cardiovascular Events on Hemodialysis Patients
NCT00530595 ·Status: COMPLETED ·Phase: NA
-
Effect of Add-on Spironolactone to Losartan Versus Losartan Alone on Peritoneal Membrane Among Peritoneal Dialysis Patients
NCT03953950 ·Status: UNKNOWN ·Phase: PHASE4
-
Aldosterone Blockade in Chronic Kidney Disease: Influence on Arterial Stiffness and Kidney Function
NCT01100203 ·Status: TERMINATED ·Phase: PHASE3
-
Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease
NCT03020303 ·Status: COMPLETED ·Phase: PHASE3
-
Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria
NCT00369538 ·Status: SUSPENDED ·Phase: PHASE4
-
Spironolactone for Reducing Proteinuria in Diabetic Nephropathy
NCT00498537 ·Status: COMPLETED ·Phase: NA
-
L-Arginine and Spironolactone Trial in Dialysis-Dependent ESRD
NCT01855334 ·Status: WITHDRAWN ·Phase: PHASE4
-
Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency
NCT00630708 ·Status: TERMINATED ·Phase: NA
-
Comparison of the Role of Losartan Alone vs Hydrochlorothiazide Plus Losartan
NCT06491940 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Spironolactone Safety in Dialysis Patients
NCT00328809 ·Status: WITHDRAWN ·Phase: PHASE4
-
Optimalization of Nephroprotection Using Agents Inhibiting Renin-Angiotensin-Aldosterone System
NCT00528385 ·Status: COMPLETED ·Phase: NA
-
Attenuation of Cardiac Effects of Arteriovenous Fistula Creation With Losartan
NCT00602004 ·Status: COMPLETED ·Phase: NA
-
Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure
NCT00527059 ·Status: UNKNOWN ·Phase: PHASE4
-
Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal Insufficiency
NCT01172431 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy
NCT03502031 ·Status: UNKNOWN ·Phase: PHASE4
-
The Effect of Enalapril, Losartan or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients
NCT05232370 ·Status: COMPLETED ·Phase: PHASE2
-
Mineralocorticoid Receptor Antagonists in End Stage Renal Disease
NCT01691053 ·Status: COMPLETED ·Phase: PHASE2
-
Losartan in Decompensated Heart Failure
NCT01857999 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Spironolactone Combination Therapy on Proteinuria, Kidney Function, and Blood Pressure
NCT01667614 ·Status: COMPLETED ·Phase: PHASE2
-
Removal of Beta Blocker Drugs by Hemodialysis
NCT03361280 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus
NCT00419835 ·Status: COMPLETED ·Phase: PHASE4
-
Is Spironolactone Safe and Effective in the Treatment of Cardiovascular Disease in Mild Chronic Renal Failure?
NCT00291720 ·Status: COMPLETED ·Phase: PHASE2
-
Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS
NCT04643691 ·Status: TERMINATED ·Phase: PHASE2
-
CR Aim #2 - AT1 Receptor Blockade & ACE Inhibition Effect on Humoral Function
NCT01678794 ·Status: COMPLETED ·Phase: PHASE1/PHASE2