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Effect of Pre- and Probiotics on P-cresol Plasma Levels in Patients Bearing a Kidney Allograft

NCT02179229 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2014-07-02

No results posted yet for this study

Summary

The purpose of this study is to establish whether a short treatment with the synbiotic combination Probinul neutro® may decrease the plasma concentration of the uremic toxin p-cresol in patients bearing a kidney allograft. The effect of this treatment on plasma levels of immunosuppressant drugs will be evaluated as well.

Conditions

  • Renal Insufficiency, Chronic

Interventions

DIETARY_SUPPLEMENT

CONTROL

Placebo will be taken at home for four weeks as 5 g powder packets to be dissolved in water three times a day far from meals.

DIETARY_SUPPLEMENT

SYNBIOTIC

Probinul Neutro® will be taken at home for four weeks as 5 g powder packets to be dissolved in water three times a day far from meals.

Sponsors & Collaborators

  • Federico II University

    lead OTHER

Principal Investigators

  • Bruna Guida, MD · Federico II University of Naples

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2015-06-30
Completion
2015-08-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02179229 on ClinicalTrials.gov