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Immune Responses to the Flu Shot During Pregnancy

NCT02148874 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 287

Last updated 2019-09-24

Study results available
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Summary

This study will examine effects of everyday life stress and obesity on immune responses to influenza virus vaccine (the flu shot) during pregnancy. Following vaccination, antibody levels against influenza (the flu) increase. Higher antibody levels indicate better immune protection from influenza. In addition to providing protection from the flu for yourself, being vaccinated during pregnancy may protect your baby from the flu during the first six months of life during which time infants cannot be vaccinated. Our primary goals are to determine whether greater life stress and obesity reduce 1) antibody responses to the flu shot in women and 2) antibody levels in the newborn at the time of delivery.

Conditions

  • Pregnancy

Interventions

BIOLOGICAL

influenza virus vaccination

comparison of immune responses to the flu vaccine in obese and non-obese populations

Sponsors & Collaborators

  • Lisa Christian

    lead OTHER

Principal Investigators

  • Lisa M. Christian, PhD · Ohio State University

Eligibility

Min Age
18 Years
Max Age
42 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2017-05-31
Completion
2019-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02148874 on ClinicalTrials.gov