Menstrual Phase and Postoperative Pain

Summary

Fluctuations of female sex hormones during the menstrual cycle influence pain perception. Endogenous pain is pronounced in the follicular phase of the menstrual cycle. The investigators tested the primary hypothesis that the women having surgery during their follicular phase have more acute pain and require more opioids than those in the luteal phase, and secondarily the investigators tested that women who have surgery during their follicular phase have more incisional pain at 3 month postoperatively.

Conditions

• Acute Postoperative Pain
• Chronic Postoperative Pain

Interventions

OTHER

HAD scale

The anxiety/depression scale (HAD) was used to assess anxiety and depression.

OTHER

The SF 12 test

The SF 12 test (SHORT FORM 12) was used to evaluate quality of life.

OTHER

Visual analogue score

Visual analogue score vas used to evaluate pain.

Sponsors & Collaborators

• Aydin Adnan Menderes University

  lead OTHER

Principal Investigators

• Betul Kozanhan, Specialist Doctor · Konya Education and Research Hospital, Anesthesiology and Reanimation Department, Konya; Turkey

• Ayse Ilksen Egilmez, Specialist Doctor · Konya Education and Research Hospital, Anesthesiology and Reanimation Department, Konya; Turkey

• Aykut Soyder, Assistant Professor · Adnan Menderes University Medical Faculty, General Surgery Department, Aydin; Turkey

• Fabrizio Galimberti, Medical Student · Cleveland ClinicLernerCollege of Medicine, Cleveland, Ohio

• Daniel I. Sessler, Professor and Ch · Department of Outcomes Research, Cleveland Clinic

• Alparslan Turan, Associate Professor · Associate Professor of Anesthesiology, Department of Outcomes Research, Cleveland Clinic

• Osman Nuri Aydın, Professor · Adnan Menderes University Medical Faculty, Anesthesiology and Reanimation Department, Aydin; Turkey

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

60 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2012-08-31

Primary Completion

2013-11-30

Completion

2013-11-30

Countries

• Turkey (Türkiye)

Study Locations