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Efficacy Study of IV Ibuprofen vs IV Acetaminophen Post Surgical Extraction

NCT02133326 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 67

Last updated 2017-01-20

No results posted yet for this study

Summary

This study will compare how effective a single dose of an intravenous (IV) ibuprofen is when compared to single dose of IV acetaminophen in reducing pain. We will administer this study medication thirty minutes prior to removal of wisdom teeth. We want to see if administering these drugs prior to surgery may reduce post-operative pain.

Administration of nonsteroidal anti-inflammatory drug before the onset of inflammation during surgery will reduce postoperative pain following third molar extraction when compared to the acetaminophen group. Subjects receiving nonsteroidal anti-inflammatory drug will consume less opioid medications compared to those receiving preemptive acetaminophen.

Conditions

  • Impacted Wisdom Teeth

Interventions

DRUG

Caldolor

Subject will be given Caldolor by IV prior to surgery.

DRUG

Ofirmev

Subject will be given Ofirmev prior to surgery.

Sponsors & Collaborators

  • Tufts University School of Dental Medicine

    lead OTHER

Principal Investigators

  • Archana Viswanath, BDS,MS · Tufts University School of Dental Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2017-01-31
Completion
2017-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02133326 on ClinicalTrials.gov