The Purpose of the Study is to Examine Whether Iron Deficiency Anemia is Associated With Increased Production of Thrombin and Whether Correction of Anemia by Providing Iron Intravenously Causes a Significant Reduction in Production of Thrombin.
NCT02129907 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 82
Last updated 2018-12-19
Summary
In total 50 subjects with iron deficiency anemia treated with intravenous iron are planned for inclusion in this trial. After signing an informed consent a blood sample will be obtained from each participant before iron treatment. The investigators will measure the thrombin generation in plasma assessed by the calibrated automated thrombogram (CAT). patient will go face to face interview and will be asked to answer structured questionnaire which will include information on demographics, clinical data ( fever, allergies , etc.) and comorbidities
Two weeks after completing intravenous iron administration additional blood samples will be taken: thrombin generation will be measured
Conditions
- Iron Deficiency Anemias
Sponsors & Collaborators
-
HaEmek Medical Center, Israel
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-10-31
- Primary Completion
- 2015-12-31
- Completion
- 2015-12-31
Countries
- Israel
Study Locations
More Related Trials
-
Comparison of the Safety and Efficacy of Intravenous Iron Versus Oral Iron in the Treatment of Anemia Secondary to Heavy Uterine Bleeding
NCT00395993 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Intravenous Ferric Carboxymaltose (FCM) in Patients With Iron Deficiency Anemia (IDA)
NCT00982007 ·Status: COMPLETED ·Phase: PHASE3
-
Trial To Evaluate the Efficacy of Intravenous Iron in Older Adults With Unexplained Anemia
NCT01309659 ·Status: TERMINATED ·Phase: PHASE2
-
IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding
NCT04205266 ·Status: RECRUITING ·Phase: PHASE4
-
IV Iron Versus Standard Treatment for Iron Deficiency Anemia in the Emergency Department
NCT05153278 ·Status: COMPLETED
-
IV Iron for the Anemia of Traumatic Critical Illness
NCT01180894 ·Status: COMPLETED ·Phase: NA
-
Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome.
NCT02031289 ·Status: COMPLETED ·Phase: PHASE4
-
Iron Prophylaxis for Anemia in Infants With Cyanotic Congenital Heart Disease
NCT00459225 ·Status: WITHDRAWN ·Phase: NA
-
Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever
NCT00736060 ·Status: COMPLETED
-
Effect of Intravenous Iron Supplementation in Reducing Allogenic Blood Transfusion
NCT04061655 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Iron Mediated Vascular Disease in Sickle Cell Anemia Patients
NCT01239901 ·Status: COMPLETED
-
Thrombin Generation in Beta-thalassemia Major
NCT04962984 ·Status: UNKNOWN ·Phase: NA
-
Efficacy and Safety of Intravenous Ferric Carboxymaltose in Pediatric Patients With Iron Deficiency Anemia and Unsatisfactory Response Oral Iron Under Study Protocol 1VIT17044
NCT04269707 ·Status: COMPLETED ·Phase: PHASE3
-
Effectiveness of Low-dose Iron Treatment in Non-anaemic Iron-deficient Women
NCT04636060 ·Status: COMPLETED ·Phase: NA
-
A Study to Observe the Causes and Treatment of Anemia in Critically Ill Children
NCT00211055 ·Status: COMPLETED
-
Single Dose Intravenous Iron Isomaltoside in Combination With Oral Iron vs Oral Iron Monotherapy in Patients With Anemia After Postpartum Haemorrhage
NCT04505514 ·Status: UNKNOWN ·Phase: PHASE4
-
Safety, Tolerability, PK and PD of Intravenous Ferric Carboxymaltose in Infants With Iron Deficiency Anemia
NCT04968379 ·Status: WITHDRAWN ·Phase: PHASE2
-
Early Antenatal Support for Iron Deficiency Anemia
NCT04278651 ·Status: RECRUITING ·Phase: PHASE4
-
Treatment of Hemochromatosis
NCT00007150 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Observational Study on the Use of IV (Intravenous) Iron Therapy Among Subjects With Iron Deficiency Anemia
NCT01984554 ·Status: COMPLETED
-
Safety of FCM vs. Standard of Care in Treating Iron Deficiency Anemia in Heavy Uterine Bleeding and Post Partum Patients
NCT00548860 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical and Laboratory Investigation of Humans With Informative Iron or Erythroid Phenotypes
NCT00102245 ·Status: TERMINATED
-
Intravenous Iron in paTients With Heart failURe and Reduced Ejection fracTion (HFREF) pLus Iron dEficiency
NCT03079518 ·Status: COMPLETED ·Phase: PHASE2
-
Erythrocytapheresis Versus Phlebotomy as Maintenance Therapy in Hereditary Hemochromatosis (HH) Patients
NCT01398644 ·Status: UNKNOWN ·Phase: PHASE3
-
Effect Of Intravenous Iron Versus Placebo On Muscle Oxidative Capacity And Physical Performance in Premenopausal Women
NCT01374776 ·Status: COMPLETED ·Phase: PHASE4