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A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

NCT02118922 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 168

Last updated 2025-11-06

No results posted yet for this study

Summary

We have developed novel Brillouin microscopy and we are testing its potential for keratoconus and ectasia diagnostics. We plan to perform axial scans of the cornea in human volunteers in order to compare biomechanical properties of Keratoconus vs. Normal corneas and compare biomechanical properties of post-LASIK ectasia vs. normal corneas.

Conditions

  • Keratoconus
  • Ectasia
  • Crosslinking
  • Fuchs' Endothelial Dystrophy

Interventions

PROCEDURE

Brillouin imaging

Sponsors & Collaborators

  • Harvard Medical School (HMS and HSDM)

    collaborator OTHER

  • Massachusetts General Hospital

    lead OTHER

Principal Investigators

  • Andy Yun, PhD · Masachusetts General Hospital

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02118922 on ClinicalTrials.gov