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The Effect of EPLerenone on Ischemia Reperfusion Injury in Human myoCARDium

NCT02118753 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2016-01-12

No results posted yet for this study

Summary

In the laboratory, the researchers will investigate whether the drug eplerenone improves contractile function after ischemia and reperfusion in heart tissue.

Conditions

  • Ischemia-reperfusion Injury

Interventions

DRUG

Eplerenone

eplerenone administered ex vivo (to the organ bath in which human atrial tissue is exposed)

Sponsors & Collaborators

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Niels P. Riksen, Dr · Radboud University Medical Center

  • Henri A. van Swieten, Prof dr ir · Radboud University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2015-12-31
Completion
2016-01-31

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02118753 on ClinicalTrials.gov