Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
NCT02109770 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 216
Last updated 2019-08-26
Summary
The purpose of this study is to collect blood from families with a child who has been diagnosed with a chromosomal disorder including microdeletions in order to further develop a non-invasive prenatal screening test based on fetal DNA isolated from maternal blood.
Conditions
- Microdeletion Syndromes
- Trisomy 21
- Trisomy 18
- Trisomy 13
- Sex Chromosome Abnormalities
Sponsors & Collaborators
-
Natera, Inc.
lead INDUSTRY
Principal Investigators
-
Kim Martin, MD · Natera, Inc.
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-31
- Primary Completion
- 2019-06-30
- Completion
- 2019-08-31
Countries
- United States
Study Locations
More Related Trials
-
Clinical Performance of NIPT in Multiple Gestation Pregnancies
NCT04488393 ·Status: COMPLETED
-
Non-Invasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker
NCT00770458 ·Status: COMPLETED
-
Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
NCT02226315 ·Status: TERMINATED
-
Non-Invasive Determination of Fetal Chromosome Abnormalities
NCT00891852 ·Status: UNKNOWN
-
Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy
NCT01429389 ·Status: RECRUITING
-
Non-Invasive Screening for Fetal Aneuploidy
NCT00847990 ·Status: COMPLETED
-
Non-Invasive Screening for Fetal Aneuploidy
NCT02317965 ·Status: UNKNOWN
-
Prenatal Screening for Down Syndrome With DNAFirst
NCT01966991 ·Status: COMPLETED
-
Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
NCT01052688 ·Status: COMPLETED
-
Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker
NCT00971334 ·Status: COMPLETED
-
Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood
NCT04285814 ·Status: COMPLETED
-
Prenatal Test for Fetal Aneuploidy Detection
NCT01256606 ·Status: COMPLETED
-
PErsonalized Genomics for Prenatal Abnormalities Screening USing Maternal Blood
NCT03831256 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A New Prenatal Blood Test for Down Syndrome
NCT00877292 ·Status: COMPLETED
-
Clinical Evaluation of the SEQureDx Trisomy Test in Low Risk Pregnancies
NCT01597063 ·Status: COMPLETED
-
Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders
NCT06147414 ·Status: RECRUITING
-
Expanded NIPT for Pregnancy Complications
NCT04311749 ·Status: COMPLETED
-
Development of an Optimal Approach to Return of Results for Next-generation Sequencing for Prenatal Diagnosis
NCT02255825 ·Status: WITHDRAWN ·Phase: NA
-
Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
NCT01555346 ·Status: COMPLETED
-
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
NCT00064597 ·Status: UNKNOWN
-
Non Invasive Prenatal Testing (NIPT) of Single-gene Disorders
NCT02339402 ·Status: UNKNOWN
-
Trisomy of Chromosome 21 Diagnosis by High Output Sequencing
NCT01118507 ·Status: COMPLETED
-
Development of a Non-invasive Prenatal Test
NCT01451684 ·Status: COMPLETED
-
Biochemical Markers and 2 and 3D Ultrasound to ID Maternal & Fetal Complications
NCT01404221 ·Status: TERMINATED
-
Down Syndrome Screening Based on Dried Blood Spots and Cell-free Fetal DNA
NCT01837979 ·Status: UNKNOWN