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Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy

NCT02106559 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2019-03-21

No results posted yet for this study

Summary

This pilot clinical trial studies photodynamic therapy during surgery in treating patients with pleural (the protective lining or membrane that covers the lungs and chest cavity) malignancy. Photodynamic therapy is an anti-cancer treatment that combines a photosensitizer (a substance that makes cells more sensitive to light), such as porfimer sodium, together with oxygen and visible light to kill tumor cells and/or damage the tumor's blood supply. Intraoperative (during surgery) photodynamic therapy may kill any tumor cells that remain after surgery.

Conditions

  • Stage III Malignant Mesothelioma
  • Stage IIIB Non-small Cell Lung Cancer
  • Stage IV Malignant Mesothelioma
  • Stage IV Non-small Cell Lung Cancer

Interventions

DRUG

porfimer sodium

Given IV

PROCEDURE

therapeutic conventional surgery

Undergo tumor resection and/or radical pleurectomy

DRUG

photodynamic therapy

Undergo PDT

Sponsors & Collaborators

  • Ohio State University Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Meng Welliver · Ohio State University Comprehensive Cancer Center

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-04
Primary Completion
2016-01-29
Completion
2016-01-29

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02106559 on ClinicalTrials.gov