Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy

Summary

There are limited therapeutical options for patients with secondary dystonia due to cerebral palsy. Pharmacotherapy is often without effect, or side effects are severe. Meanwhile deep brain stimulation (DBS) has proven to be a safe and effective therapy for patients with parkinson´s disease or primary / idiopathic dystonia. Experiences with DBS in patients with dyskinetic cerebral palsy are limited with heterogeneous data.

With STIM-CP we investigate the effect of DBS on quality of life in young patients with a dyskinetic movement disorder (dyskinetic cerebral palsy) due to perinatal hypoxic brain injury. Additionally, the effect of DBS on motor development, speech, memory, attention, cognition and pain perception will be assessed.

Conditions

• Dyskinetic Cerebral Palsy Due to Perinatal Hypoxia

Sponsors & Collaborators

• University Hopsital Schleswig Holstein Campus Lübeck

  collaborator OTHER

• Boston Scientific Corporation

  collaborator INDUSTRY

• University Hsopital of Magdeburg

  collaborator UNKNOWN

• University Hospital of Munich

  collaborator UNKNOWN

• Schoen Klinik Vogtareuth

  collaborator UNKNOWN

• University Hospital of Tübingen

  collaborator UNKNOWN

• Heinrich-Heine University, Duesseldorf

  collaborator OTHER

• Hannover Medical School

  collaborator OTHER

• University Hospital of Kiel

  collaborator UNKNOWN

• University Hospital of Würzburg

  collaborator UNKNOWN

• University Hospital of Freiburg

  collaborator UNKNOWN

• University Hospital Berlin Charite

  collaborator UNKNOWN

• University Hospital of Cologne

  lead OTHER

Principal Investigators

• Anne Koy, MD · University Hospital Cologne, Germany

Eligibility

Min Age

7 Years

Max Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-03-04

Primary Completion

2020-03-10

Completion

2021-12-31

Countries

• Germany

Study Locations