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The Role of Ninjurin-1 During Systemic Inflammation

NCT02079597 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2014-09-03

No results posted yet for this study

Summary

* With the underlying study the investigators address the question if Ninjurin-1 (Ninj1) expression is altered in patients with systemic inflammatory response syndrome (SIRS) in comparison to healthy volunteers.
* The adhesion molecule Ninj1 is induced following nerve injury where it contributes to nerve generation. Besides it is described to facilitate leukocyte migration especially in the nervous system.
* The investigators hypothesize that Ninj1 expression is increased in SIRS patients, which will fortify its impact during inflammation and the transferability from bench to bedside.

Conditions

  • Ninj1 Expression
  • SIRS

Sponsors & Collaborators

  • Dr. Patrick Meybohm, M.D.

    lead OTHER

Principal Investigators

  • Patrick Meybohm, MD · Department of Anesthesiology, University Hospital Frankfurt

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2014-06-30
Completion
2014-09-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02079597 on ClinicalTrials.gov