Prasugrel and Ticagrelor in ST-segment Elevation Myocardial Infarction
NCT02075125 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 39
Last updated 2017-08-18
Summary
To compare efficacy and safety of prasugrel and ticagrelor in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.
Conditions
- ST-Segment Elevation Myocardial Infarction
Interventions
- DRUG
-
Prasugrel 60 mg
Patient administer prasugrel 60 mg as loading dose followed by 10 mg/day as maintenance dose.
- DRUG
-
Ticagrelor 180 mg
Patients administer ticagrelor 180 mg as loading dose followed by 90 mg bid as maintenance dose.
Sponsors & Collaborators
-
Dong-A University
lead OTHER
Principal Investigators
-
Moo Hyun Kim, M.D. · Dong-A University Hospital, Busan, Republic of Korea
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2015-04-30
- Completion
- 2015-04-30
Countries
- South Korea
Study Locations
More Related Trials
-
Reducing Micro Vascular Dysfunction in Acute Myocardial Infarction by Ticagrelor
NCT02422888 ·Status: UNKNOWN ·Phase: PHASE4
-
Prasugrel 5 mg vs. Ticagrelor 60 mg in CHIP (E5TION)
NCT04734353 ·Status: UNKNOWN ·Phase: PHASE4
-
Facilitation Through Aggrastat By drOpping or Shortening Infusion Line in Patients With ST-segment Elevation Myocardial Infarction Compared to or on Top of PRasugrel Loading dOse
NCT01336348 ·Status: COMPLETED ·Phase: PHASE3
-
Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study
NCT03016611 ·Status: UNKNOWN ·Phase: PHASE4
-
PraSugrel vs TicagrElor in ST-Elevation Myocardial Infarction paTients With Diabetes Mellitus
NCT01531114 ·Status: COMPLETED ·Phase: PHASE3
-
A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)
NCT01347580 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Ticagrelor on No-reflow in Patients With Acute ST-segment Elevation Myocardial Infarction
NCT02798874 ·Status: UNKNOWN ·Phase: NA
-
Ticagrelor Monotherapy in PAtients Treated With New-generation Drug-eluting Stents for Acute Coronary Syndrome; T-PASS Trial
NCT03797651 ·Status: UNKNOWN ·Phase: NA
-
Early Versus Late Loading of Ticagrelol in Patients With STEMI
NCT04267224 ·Status: UNKNOWN
-
3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI
NCT04570345 ·Status: UNKNOWN ·Phase: PHASE4
-
High (100mg) Versus Standard (60mg) Loading Dose of Prasugrel in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
NCT01835353 ·Status: COMPLETED ·Phase: PHASE3
-
Differential Effect of Ticagrelor Versus Prasugrel on the Adenosine-induced Coronary Vasodilatory Responses in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
NCT01642966 ·Status: COMPLETED ·Phase: PHASE4
-
Impact of Ticagrelor on the Endothelial Healing Following Drug-eluting Stent Implantation in the Patients With Acute Coronary Syndrome
NCT02037412 ·Status: TERMINATED ·Phase: PHASE4
-
Standard (180mg) Versus Double (360mg) Loading Dose of Ticagrelor in Patients With ST-elevation Myocardial Infarction (STEMI), Undergoing Primary Percutaneous Coronary Intervention (PCI)
NCT01575795 ·Status: COMPLETED ·Phase: PHASE4
-
Cangrelor vs. Ticagrelor for Early Platelet Inhibition in STEMI
NCT03182855 ·Status: UNKNOWN ·Phase: PHASE4
-
Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)
NCT02494895 ·Status: UNKNOWN ·Phase: PHASE4
-
Platelet Reactivity Inhibition Following Ticagrelor Loading Dose and One Year Outcome
NCT02428725 ·Status: COMPLETED ·Phase: NA
-
Ticagrelor Monotherapy After Stenting
NCT05149560 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective, Randomized Trial of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome
NCT01944800 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study
NCT01916902 ·Status: WITHDRAWN ·Phase: PHASE4
-
OraL Crushed and dIspersed Ticagrelor 180mg Compared to Whole Tablets of eQUal Dose in STEMI Patients unDergoing Primary PCI: a Pharmacokinetic/Pharmacodynamic Study (the LIQUID Study)
NCT02046486 ·Status: COMPLETED ·Phase: PHASE4
-
Ticagrelor for PCI Post Thrombolysis
NCT01930591 ·Status: COMPLETED ·Phase: PHASE3
-
Sub Lingual Versus Traditional Oral Administration of Ticagrelor in Acute Coronary Syndrome/Non ST-elevation Myocardial Infarction - A Platelet Reactivity Study
NCT02402400 ·Status: COMPLETED ·Phase: PHASE4
-
The Effects of Facilitated Percutaeous Coronary Intervention in Acute Myocardial Infarction
NCT00611169 ·Status: COMPLETED ·Phase: PHASE4
-
Rapid P2Y12 Receptor Inhibition Attenuates Inflammatory Cell Infiltration in Thrombus Aspirated From the STEMI Patients
NCT02639143 ·Status: COMPLETED ·Phase: PHASE4