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Detecting Lung Infections Through Vibration

NCT02056860 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16

Last updated 2016-03-16

No results posted yet for this study

Summary

The purpose of this study is to test a lung air vibrator device for vibrating air inside the lung. This exploratory diagnostic trial will test a novel and non-invasive means of detecting lower airway infections using exhaled breath sample.

Conditions

  • Lung Infection

Interventions

PROCEDURE

Group 1 will receive 15 Hz

Group 1 (n=30), these subjects will receive 10 minutes of High Frequency Oscillation at 15 Hz at .75 cm on day 1. Then will have a 24 hour washout. On day 2 will receive 10 minutes of low Frequency Oscillation at 15 Hz at 1.25 cm.

PROCEDURE

Group 2 will receive 30 Hz

Group 2 (n=30), these subjects will receive 10 minutes of High Frequency Oscillation at 30 Hz at .75 cm on day 1. Then will have a 24 hour washout. On day 2 will receive 10 minutes of low Frequency Oscillation at 30 Hz 1.25 cm.

PROCEDURE

Group 3 will receive 60 Hz

Group 3 (n=30), these subjects will receive 10 minutes of High Frequency Oscillation at 60 Hz .75 cm on day 1. Then will have a 24 hour washout. On day 2 will receive 10 minutes of low Frequency Oscillation at 60 Hz at 1.25 cm.

PROCEDURE

Group 4 will receive 100 Hz

Group 4 (n=30), these subjects will receive 10 minutes of High Frequency Oscillation at 100 Hz at .75 cm on day 1. Then will have a 24 hour washout. On day 2 will receive 10 minutes of low Frequency Oscillation at 100 Hz at 1.25 cm.

PROCEDURE

Phase II Optimal Frequency

Participants in Phase II will undergo 10 minutes of HFO at the optimal frequency as determined during Phase I.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Erin P Silverman, PhD · University of Florida

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02056860 on ClinicalTrials.gov