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Study of Pain Processing in Experienced Yoga Practitioners

NCT02055235 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 47

Last updated 2017-07-07

No results posted yet for this study

Summary

Background:

\- Different people perceive the same pain differently. Mood, attention, stress, and personality affect how we feel pain. Researchers want to know whether people who do yoga perceive pain differently than people who do not practice yoga, meditation, or martial arts. They also want to study if cortisol, a stress hormone, relates to pain or brain differences.

Objective:

\- To study the effects of yoga on the body s stress response, pain perception, and the brain s structure and pain response.

Eligibility:

* Right-handed adults 30 years and older who practice yoga regularly.
* Healthy right-handed volunteers 30 years and older who do at least mild exercise but no yoga or martial arts.

Design:

* Visit 1: Participants will be screened with medical history and physical exam. They will have blood and urine tests and electrocardiogram to measure heart activity.
* At home, participants will wear a heart monitor for 1 day and collect 5 saliva samples daily for seven days.
* Visit 2: Participants will undergo tests in a chair or in a mock MRI machine. They will lie on a table that slides into a cylinder.
* A heating device will be placed on their leg and heated periodically for few seconds at a time.
* They will give saliva samples.
* Heart rate, respiration, etc. will be monitored.
* They will fill out questionnaires.
* Visit 3: Participants will answer questions and repeat Visit 2 tests. Tests will be done in the real MRI machine. The scanner makes loud knocking sounds. Participants will get earplugs. Participants will be in the scanner about 1 hour with a coil over their head.

Conditions

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH

  • National Institute of Nursing Research (NINR)

    collaborator NIH

  • National Center for Complementary and Integrative Health (NCCIH)

    lead NIH

Principal Investigators

  • Mary C Bushnell, Ph.D. · National Center for Complementary and Integrative Health (NCCIH)

Eligibility

Min Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-01-27
Primary Completion
2015-10-19
Completion
2016-10-12

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02055235 on ClinicalTrials.gov