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Low-level Laser Therapy on Inflammatory Mediators During Chemotherapy-induced Oral Mucositis

NCT02050373 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2021-01-22

Study results available
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Summary

The aim of the study is to evaluate the effect of low-level laser therapy (LLLT) on the severity of oral mucositis (OM) and inflammatory mediators (pro- and anti-inflammatory cytokines, metalloproteinases and growth factors) levels in saliva and blood; furthermore, analyze the effect of LLLT in product modulation of oxidative stress and cell damage from the oral mucosa transplant patients.

Conditions

  • Oral Mucositis

Interventions

RADIATION

Low-Level laser

Application of laser therapy in low power mucosa jugal right and left upper and lower labial mucosa, floor of the mouth, tongue side of the right and left and belly of the tongue.

Sponsors & Collaborators

  • Federal University of Minas Gerais

    collaborator OTHER

  • Araujo Jorge Hospital

    collaborator OTHER

  • Universidade Federal de Goias

    lead OTHER

Principal Investigators

  • Geisa BL Silva, Master · Universidade Federal de Goias

  • Aline C Batista, Doctor · Universidade Federal de Goias

  • Daniella RN Salvador · Universidade Federal de Goias

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2012-11-30
Completion
2017-02-28

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02050373 on ClinicalTrials.gov