Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study
NCT02050269 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2025-12-22
Summary
The objective of this study is to assess the feasibility of estimating the clearance of iohexol as an indirect measure of glomerular filtration rate in patients with unstable renal function in the intensive care unit through analysis of rich iohexol plasma kinetics.
Conditions
- Acute Circulatory Failure
Interventions
- DRUG
-
Iohexol
Iohexol, 300 mg/mL
Sponsors & Collaborators
-
University Hospital, Tours
lead OTHER
Principal Investigators
-
Stephan EHRMANN, MCU-PH · University Hospital, Tours
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2016-06-30
- Completion
- 2016-06-30
Countries
- France
Study Locations
More Related Trials
-
Renal Function Measurements in Children
NCT01092260 ·Status: COMPLETED
-
Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis
NCT00752245 ·Status: WITHDRAWN ·Phase: NA
-
Prognostic Role of the Uremic Toxin Indoxyl Sulfate on Vascular and Cardiac Functions During Acute Kidney Injury
NCT05659589 ·Status: RECRUITING ·Phase: NA
-
Evaluation of the Performance of Glomerular Filtration Rate Measurement Using CT Urography in Patients With a GFR Below 60 mL/Min/1.73 m²
NCT07042698 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Creatinine Clearance as a Predictor of Successful Withdrawl of Continuous Renal Replacement Therapy in Intensive Care
NCT04375358 ·Status: COMPLETED
-
Intra Individual Evaluation of Uremic Toxin Levels in Hemodialysed Patients
NCT02480699 ·Status: COMPLETED ·Phase: NA
-
The Efficacity of Hemodiafiltration Versus Hemofiltration for Renal Insufficiency During Intensive Care
NCT01403220 ·Status: COMPLETED ·Phase: NA
-
Estimation of Glomerular Filtration Flow in Patients of Resuscitation Under Extra-bodily Assistance
NCT03525483 ·Status: UNKNOWN ·Phase: NA
-
Hemodynamic Effects of Blood Flow Variation in Continuous Renal Replacement Therapy
NCT03078504 ·Status: TERMINATED ·Phase: NA
-
Acute Kidney Injury in Non-Critical Care Setting: Elaboration and Validation of an In-hospital Death Prognosis Score
NCT04242615 ·Status: COMPLETED
-
Outcomes of Critically Ill Patients With Severe Acute Kidney Injury Requiring Renal Replacement Therapy
NCT02897310 ·Status: COMPLETED
-
Impact of the Characteristics of Acute Renal Failure in Intensive Care on the Long-term Renal Prognosis: Prospective Multicenter Cohort Study
NCT05247502 ·Status: RECRUITING
-
Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure
NCT03536195 ·Status: COMPLETED
-
Effects of HIgh Volume COntinuous REnal Replacement Therapy in Patients With Septic Acute Kidney Injury
NCT01191905 ·Status: COMPLETED ·Phase: NA
-
Interest of Urinary Oxygen Partial Pressure (PO2u) in Predicting the Onset or Recovery of Acute Renal Failure During Shock States - OXYpi Study
NCT06320509 ·Status: RECRUITING ·Phase: NA
-
Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?
NCT03547414 ·Status: UNKNOWN
-
Pharmacokinetic Evaluation of Fluoroquinolone Antibiotics Administered Intravenously in Intensive Care Patients With Normal Renal Function and With Renal Hyperfiltration
NCT01109823 ·Status: COMPLETED ·Phase: PHASE3
-
Oxidative Stress and Circulating Nuclear DNA (cfDNA) in Acute Kidney Injury and Continuous Renal Replacement Therapies.
NCT06646328 ·Status: TERMINATED ·Phase: PHASE4
-
Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients
NCT00971971 ·Status: COMPLETED ·Phase: NA
-
Observational Study of Blood Pressure Measurements and Continuous Dialysis
NCT01286506 ·Status: TERMINATED
-
Investigations Into Sepsis-associated Acute Kidney Injury
NCT05694624 ·Status: RECRUITING
-
The Relation Between the Renal Resistive Index and Glomerular Hyper Filtration
NCT02560402 ·Status: COMPLETED
-
Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker
NCT05542927 ·Status: UNKNOWN
-
Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units
NCT04459975 ·Status: UNKNOWN
-
The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance
NCT04198168 ·Status: TERMINATED