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Prostate Testing for Cancer and Treatment

NCT02044172 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 82849

Last updated 2022-11-14

No results posted yet for this study

Summary

RATIONALE: Radical prostatectomy is surgery to remove the entire prostate. Radiation therapy uses high-energy x-rays or other types of radiation to kill tumor cells. Sometimes the tumor may not need treatment until it progresses. In this case, active surveillance may be sufficient. It is not yet known which treatment regimen is more effective for localized prostate cancer.

PURPOSE: This randomized phase III trial is studying active monitoring to see how well it works compared with radical prostatectomy or radiation therapy in treating patients with localized prostate cancer.

Conditions

Interventions

PROCEDURE

Radical prostatectomy

radical prostatectomy

RADIATION

Conformal radiation therapy

Conformal radiation therapy, external beam

OTHER

Active monitoring

Active monitoring of Prostate specific antigen levels and disease surveillance

Sponsors & Collaborators

  • University of Bristol

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Freddie C Hamdy · University of Oxford

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
69 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-06-01
Primary Completion
2020-11-14
Completion
2027-03-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02044172 on ClinicalTrials.gov