Study of Optimizing Neoadjuvant Regimens in Subtypes of Breast Cancer
NCT02041338 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2014-11-25
Summary
There are no standard neodjuvant regimens adapted according to the different subtypes of breast cancer. This is a phase 2, randomized study to evaluate several regimens in different subtypes of breast cancer.
Conditions
- Breast Cancer
- Neoadjuvant Chemotherapy
Interventions
- DRUG
-
Paclitaxel and carboplatin
- DRUG
- DRUG
-
Epirubicin and Paclitaxel
Sponsors & Collaborators
-
Chinese Academy of Medical Sciences
lead OTHER
Principal Investigators
-
Binghe Xu, MD · Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2016-12-31
- Completion
- 2017-12-31
Countries
- China
Study Locations
More Related Trials
-
A Study for the Neoadjuvant Treatment of Breast Cancer
NCT05420454 ·Status: RECRUITING ·Phase: PHASE4
-
Minus Anthracycline or Short-Term Versus Epirubicin and Cyclophosphamide Followed by Paclitaxel Regimen for Adjuvant Breast Cancer Therapy
NCT01314833 ·Status: COMPLETED ·Phase: PHASE3
-
Neoadjuvant Chemotherapy With Pyrotinib, Epirubicin and Cyclophosphamide Followed by Taxanes and Trastuzumab for HER-2+ Breast Cancer
NCT04290793 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Palbociclib + Letrozole Versus Epirubicin + Cyclophosphamide and Sequential Docetaxel as Neoadjuvant Chemotherapy
NCT04137640 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Neoadjuvant Chemotherapy With WH002 in Women With HER2-negative Breast Cancer
NCT06513364 ·Status: COMPLETED ·Phase: PHASE1
-
Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer
NCT04126525 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Tailored Neoadjuvant Chemotherapy for Stage II/III Breast Cancer With Tumor Size More Than 2 cm
NCT00776724 ·Status: COMPLETED ·Phase: PHASE3
-
A Study on Neoadjuvant Therapy for Her-2 Positive Breast Cancer and the Prognosis by Detecting CTCs
NCT02510781 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Study of Nab-paclitaxel Plus Carboplatin in Breast Cancer
NCT01625429 ·Status: UNKNOWN ·Phase: PHASE2
-
Adjuvant Albumin-bound Paclitaxel Versus Taxanes in Breast Cancer: a Real-world Study
NCT05287308 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Neoadjuvant Therapy Study Guided by Drug Screening in Vitro for Human Epidermal Growth Factor Receptor 2 (HER2) Negative Early Breast Cancer Patients
NCT04836156 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Neoadjuvant Study of Sequential Eribulin Followed by FAC Compared to Sequential Paclitaxel Followed by FEC in Early Stage Breast Cancer Not Overexpressing HER-2
NCT01593020 ·Status: COMPLETED ·Phase: PHASE2
-
Adjuvant Therapy Choice for Non-pCR HER2 Positive Early Breast Cancer After Neoadjuvant Therapy
NCT06693037 ·Status: RECRUITING
-
Neoadjuvant Study With Pyrotinib and Trastuzumab and Abraxane in Patients With HER2-enriched Breast Cancer
NCT05659056 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer
NCT03756064 ·Status: UNKNOWN ·Phase: NA
-
Neoadjuvant Effect of Albumin Binding Paclitaxel Compared With Common Paclitaxel in Breast Cancer:an Observational Single Center Study of Clinical Efficacy in Adjuvant Chemotherapy
NCT05636644 ·Status: UNKNOWN
-
A Study of Neoadjuvant TCHpy(Pyrotinib ,Trastuzumab,Carboplatin and Paclitaxel)for ER+/HER2+ Breast Cancer
NCT06000917 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant or Adjuvant Epirubicin, Cyclophosphamide, and Paclitaxel in Treating Women With Stage I, Stage II, or Stage III Breast Cancer
NCT00072319 ·Status: COMPLETED ·Phase: PHASE2
-
Apatinib in Neoadjuvant Therapy for Patients With Breast Cancer
NCT03580395 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Nab-paclitaxel Compared With Docetaxel Followed by Anthracyclines and Cyclophosphamide in the Neoadjuvant Breast Cancer
NCT04182568 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study of Gemcitabine, Epirubicin, and Paclitaxel Combination Chemotherapy Given Before Surgery to Patients With Locally Advanced Breast Cancer
NCT00378313 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer
NCT05076695 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Oral Paclitaxel Plus Subcutaneous Pertuzumab/Trastuzumab in Patients With HER2-positive Breast Cancer
NCT07095023 ·Status: RECRUITING ·Phase: NA
-
Trial of Adjuvant Chemotherapy in Breast Cancer Patients With Pathological Partial Response and Complete Response to Neoadjuvant Chemotherapy
NCT02879513 ·Status: UNKNOWN ·Phase: PHASE3
-
Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Docetaxel and Carboplatin in HER2 Positive Breast Cancer Patients.
NCT03735966 ·Status: COMPLETED ·Phase: PHASE2