Safety Study of VM202 to Treat Amyotrophic Lateral Sclerosis
NCT02039401 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 18
Last updated 2025-10-06
Summary
The purpose of this study is to determine the safety and tolerability of intramuscular injections of VM202 at different injection sites in people with amyotrophic lateral sclerosis.
Conditions
Interventions
- BIOLOGICAL
-
VM202
Sponsors & Collaborators
-
Helixmith Co., Ltd.
lead INDUSTRY
Principal Investigators
-
John A Kessler, MD · Northwestern University Stem Cell Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2014-03-11
- Primary Completion
- 2015-08-03
- Completion
- 2024-03-06
Countries
- United States
Study Locations
More Related Trials
-
Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification III
NCT00415519 ·Status: COMPLETED ·Phase: PHASE3
-
A Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT00444613 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
NCT06100276 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Safety of Engensis in Participants With Amyotrophic Lateral Sclerosis
NCT04632225 ·Status: COMPLETED ·Phase: PHASE2
-
Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT00424463 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis
NCT01753076 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study of NP001 in Patients With Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation
NCT02794857 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate the Safety and Efficacy of Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis
NCT06493279 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intrathecal Injection for ALS
NCT05003921 ·Status: SUSPENDED ·Phase: PHASE1
-
A Study to Evaluate the Efficacy and Safety of Different Doses of CB03-154 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT07082192 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia
NCT01064440 ·Status: COMPLETED ·Phase: PHASE2
-
An IIT Clinical Study to Evaluate the Safety and Efficacy of a Single Intrathecal Injection of RJK002 in Patients With ALS
NCT06454682 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
A Study to Evaluate the Tolerability, Safety and Efficacy of VGN-R13 in Patients with ALS
NCT06849609 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy
NCT03508947 ·Status: COMPLETED ·Phase: PHASE1
-
Treatment of Intravenous Infusion Plasma in Amyotrophic Lateral Sclerosis
NCT04454840 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT06441682 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A First in Human Study of ORT247 in Healthy Volunteers
NCT06769620 ·Status: COMPLETED ·Phase: PHASE1
-
A Long-Term Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
NCT00445172 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BIIB100 Administered Orally to Adults With Amyotrophic Lateral Sclerosis
NCT03945279 ·Status: COMPLETED ·Phase: PHASE1
-
Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS
NCT03520517 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis
NCT03427086 ·Status: COMPLETED ·Phase: PHASE2
-
Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis (ALS)
NCT01142856 ·Status: COMPLETED ·Phase: PHASE1
-
A Dose-escalation Safety Trial for Intrathecal Autologous Mesenchymal Stem Cell Therapy in Amyotrophic Lateral Sclerosis
NCT01609283 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Creatine Monohydrate in Patients With Amyotrophic Lateral Sclerosis
NCT00069186 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy
NCT02193074 ·Status: TERMINATED ·Phase: PHASE3