Trial Outcomes & Findings for Comparison of Two Programs for Weight Loss and Impact on Metabolic Syndrome (NCT NCT02023515)

NCT ID: NCT02023515

Last Updated: 2017-06-27

Results Overview

Weight change from baseline to 20 weeks

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

49 participants

Primary outcome timeframe

Weight change from baseline to 20 weeks

Results posted on

2017-06-27

Participant Flow

Participant milestones

Participant milestones
Measure
Stress Management
Approximately half of the participants will be randomized to a stress management arm. Participants will undergo Emotional Brain Training during a 90 minute session once per week for ten weeks in order to rewire the brain and improve stress management techniques. Emotional brain training: Stress management based program
Standard Behavioral Weight Loss
Half of participants will receive a standard behavioral weight loss program in 90 minute sessions once per week for 10 weeks Behavioral weight loss: Standard behavioral weight loss
Overall Study
STARTED
24
25
Overall Study
COMPLETED
23
22
Overall Study
NOT COMPLETED
1
3

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Comparison of Two Programs for Weight Loss and Impact on Metabolic Syndrome

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Stress Management
n=24 Participants
Approximately half of the participants will be randomized to a stress management arm. Participants will undergo Emotional Brain Training during a 90 minute session once per week for ten weeks in order to rewire the brain and improve stress management techniques. Emotional brain training: Stress management based program
Standard Behavioral Weight Loss
n=25 Participants
Half of participants will receive a standard behavioral weight loss program in 90 minute sessions once per week for 10 weeks Behavioral weight loss: Standard behavioral weight loss
Total
n=49 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Age, Categorical
Between 18 and 65 years
24 Participants
n=39 Participants
25 Participants
n=41 Participants
49 Participants
n=35 Participants
Age, Categorical
>=65 years
0 Participants
n=39 Participants
0 Participants
n=41 Participants
0 Participants
n=35 Participants
Age, Continuous
45.5 years
STANDARD_DEVIATION 8.0 • n=39 Participants
44.0 years
STANDARD_DEVIATION 8.8 • n=41 Participants
45.0 years
STANDARD_DEVIATION 7.9 • n=35 Participants
Sex: Female, Male
Female
20 Participants
n=39 Participants
21 Participants
n=41 Participants
41 Participants
n=35 Participants
Sex: Female, Male
Male
4 Participants
n=39 Participants
4 Participants
n=41 Participants
8 Participants
n=35 Participants
Region of Enrollment
United States
24 participants
n=39 Participants
25 participants
n=41 Participants
49 participants
n=35 Participants

PRIMARY outcome

Timeframe: Weight change from baseline to 20 weeks

Weight change from baseline to 20 weeks

Outcome measures

Outcome measures
Measure
Stress Management
n=24 Participants
Approximately half of the participants will be randomized to a stress management arm. Participants will undergo Emotional Brain Training during a 90 minute session once per week for ten weeks in order to rewire the brain and improve stress management techniques. Emotional brain training: Stress management based program
Standard Behavioral Weight Loss
n=25 Participants
Half of participants will receive a standard behavioral weight loss program in 90 minute sessions once per week for 10 weeks Behavioral weight loss: Standard behavioral weight loss
Weight Loss
1.6 kg
Standard Deviation 3.8
3.9 kg
Standard Deviation 3.3

SECONDARY outcome

Timeframe: PSS change from baseline to 20 weeks

Stress was measured by the Perceived Stress Scale (PSS). This scale measures stress on a scale of 0 to 40 points. The results are reported as a total score on the scale. Higher numbers indicate more stress than lower numbers.

Outcome measures

Outcome measures
Measure
Stress Management
n=24 Participants
Approximately half of the participants will be randomized to a stress management arm. Participants will undergo Emotional Brain Training during a 90 minute session once per week for ten weeks in order to rewire the brain and improve stress management techniques. Emotional brain training: Stress management based program
Standard Behavioral Weight Loss
n=25 Participants
Half of participants will receive a standard behavioral weight loss program in 90 minute sessions once per week for 10 weeks Behavioral weight loss: Standard behavioral weight loss
Decrease in Stress
-4.5 units on a scale
Interval -6.8 to -2.2
-1.8 units on a scale
Interval -4.5 to 0.9

Adverse Events

Stress Management

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Standard Behavioral Weight Loss

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kelly Webber, PhD, RD, LD

UKentucky

Phone: 859-257-4351

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place