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The Role of TLR-4 Polymorphisms in Children With Urinary Track Infections

NCT02021305 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 160

Last updated 2013-12-27

No results posted yet for this study

Summary

Purpose So far anatomical abnormalities (mostly congenital) were, in the majority of the patients, associated with urinary track infections. In this study the researchers will try to investigate the role of TLRs as molecular interactions between bacterial virulence and host response.

TLRs are important mediators in the development of the natural immunity against bacteria. They recognize microbial pathogen associated molecular patterns and alert the host's immune system to the presence of invading microbes

Conditions

Sponsors & Collaborators

  • Aristotle University Of Thessaloniki

    lead OTHER

Principal Investigators

  • Efimia Papadopoulou-Alataki, MD, PhD · Aristotle University Of Thessaloniki

Eligibility

Min Age
6 Months
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-02-28
Primary Completion
2014-02-28
Completion
2017-02-28

Countries

  • Greece

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02021305 on ClinicalTrials.gov