Trial Outcomes & Findings for Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed. (NCT NCT02017379)

NCT ID: NCT02017379

Last Updated: 2021-03-04

Results Overview

Whether erythromycin, metoclopramide versus control can enable visualization of the entire gastric mucosa .

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

4 participants

Primary outcome timeframe

45 minutes

Results posted on

2021-03-04

Participant Flow

The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Participant milestones

Participant milestones
Measure
Erythromycin
Intravenous erythromycin infusion (dose: 250 mg) 30 min-60 min before procedure Erythromycin
Metoclopromide
Intravenous metoclopromide infusion (dose: 10 mg) 30-60 minutes prior to endoscopy Metoclopromide
Control
no medications will be given prior to endoscopy
Overall Study
STARTED
0
0
0
Overall Study
COMPLETED
0
0
0
Overall Study
NOT COMPLETED
0
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Randomized Control Trial Comparing Prokinetics and Their Influence on Endoscopy Outcomes for Upper GI Bleed.

Baseline characteristics by cohort

Baseline data not reported

PRIMARY outcome

Timeframe: 45 minutes

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Whether erythromycin, metoclopramide versus control can enable visualization of the entire gastric mucosa .

Outcome measures

Outcome data not reported

PRIMARY outcome

Timeframe: 45 minutes

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Whether erythromycin, metoclopramide vs control can improve the quality of stomach and duodenum visualization: using the scoring system by Fossard et al

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 45 minutes

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Ability to identify the source of bleeding

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 48 hours

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Need for second-look endoscopy

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 48 hours

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

Mean number of blood units transfused

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 30 days

Population: The study was terminated and the PI has left the institution. Efforts were made to contact the PI/study team members, but were unsuccessful. No study data are available.

All cause mortality

Outcome measures

Outcome data not reported

Adverse Events

Erythromycin

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Metoclopromide

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Research Compliance Officer

Texas Tech University Health Sciences Center at El Paso

Phone: 915-215-4814

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place