Trial Outcomes & Findings for Exparel in Minimally Invasive Cardiac Surgery (NCT NCT02008370)

NCT ID: NCT02008370

Last Updated: 2019-10-04

Results Overview

The other primary endpoint of this study is the effectiveness of analgesia from the thoracotomy and chest tube site infiltrations as measured by the overall postsurgical analgesic use, (converted to morphine equivalents).

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

9 participants

Primary outcome timeframe

5 days

Results posted on

2019-10-04

Participant Flow

Participant milestones

Participant milestones
Measure
Exparel Infiltration
Exparel infiltrated into wound and chest tube sites Exparel infiltration: Exparel infiltrated into wound and chest tube sites
Overall Study
STARTED
7
Overall Study
COMPLETED
0
Overall Study
NOT COMPLETED
7

Reasons for withdrawal

Reasons for withdrawal
Measure
Exparel Infiltration
Exparel infiltrated into wound and chest tube sites Exparel infiltration: Exparel infiltrated into wound and chest tube sites
Overall Study
Lost to Follow-up
7

Baseline Characteristics

Exparel in Minimally Invasive Cardiac Surgery

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Exparel Infiltration
n=7 Participants
Exparel infiltrated into wound and chest tube sites Exparel infiltration: Exparel infiltrated into wound and chest tube sites
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
5 Participants
n=99 Participants
Age, Categorical
>=65 years
2 Participants
n=99 Participants
Age, Continuous
59 years
n=99 Participants
Sex: Female, Male
Female
5 Participants
n=99 Participants
Sex: Female, Male
Male
2 Participants
n=99 Participants
Region of Enrollment
United States
7 Participants
n=99 Participants

PRIMARY outcome

Timeframe: 5 days

Population: None of the patients completed to date 5: Lost to follow-up

The other primary endpoint of this study is the effectiveness of analgesia from the thoracotomy and chest tube site infiltrations as measured by the overall postsurgical analgesic use, (converted to morphine equivalents).

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 10 days +/- 5 days

Population: Lost of follow-up.

Overall rating of subject satisfaction with postsurgical pain control

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: First 5 post-op days

Population: Lost to follow up

Subject reported surgical pain (using an 11-point numeric rating scale ).

Outcome measures

Outcome data not reported

Adverse Events

Exparel Infiltration

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr G Trunfio

Maimonides Medical Center

Phone: 718-283-6000

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place