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The Influence of High Impact Exercise on Musculoskeletal Health in Older Men

NCT02007460 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2013-12-10

No results posted yet for this study

Summary

Osteoporotic fractures are an extremely common and serious public health issue which contribute substantially to pain, impaired mobility and morbidity in the elderly. Declines in bone strength combined with an increase risk of falls (associated with decline in muscular function with age) are the main determinants of fracture risk. Exercise that is novel and involves impact loading has the potential to improve bone strength and neuromuscular function (strength, power and balance). It is thus imperative to evaluate potential benefits of exercise in older people. The musculoskeletal responses to exercise may also be influenced by vitamin D status. It is the purpose of this study to consider the influence of a one year unilateral (one limb) high impact exercise programme on musculoskeletal health, specifically bone structure, muscle strength and power in older caucasian men. It is also the purpose of this study to determine whether this differs according to vitamin D status. The findings will reveal whether exercise can improve bone health and/or neuromuscular function, and whether improvements are dependent upon vitamin D status.

Conditions

  • Bone Strength
  • Neuromuscular Function

Interventions

BEHAVIORAL

Exercise

multidirectional unilateral hopping exercise

Sponsors & Collaborators

  • University Hospitals Leicester NHS Trust, UK

    collaborator UNKNOWN

  • University Hospitals of Derby and Burton NHS Foundation Trust

    collaborator OTHER

  • Loughborough University

    lead OTHER

Principal Investigators

  • Katherine Brooke-Wavell, PhD · Loughborough University

  • Winston Rennie, MBBS · University Hospitals Leicester NHS Trust

  • Jonathan Folland, PhD · Loughborough University

  • Greg Summers, MD · Derby University Hospitals Trust

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
65 Years
Max Age
80 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2012-01-31
Completion
2012-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02007460 on ClinicalTrials.gov