Intrapleural Administration of Bevacizumab Versus Endostar for Pleural Effusions in NSCLC
NCT02005120 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2013-12-20
Summary
Malignant pleural effusion (MPE) is a common complication of advanced non-small cell lung cancer (NSCLC). Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor (VEGF), has been shown to be efficient in suppressing the accumulation of pleural fluid. The other widely used treatment for MPE is recombinant human endostatin.
Conditions
- Non Small Cell Lung Cancer
Interventions
- DRUG
-
Intrapleural administration of bevacizumab
- DRUG
-
recombinant human endostatin
Intrapleural administration of recombinant human endostatin
Sponsors & Collaborators
-
Zhejiang University
lead OTHER
Principal Investigators
-
Qiong Zhao, PhD · The First Affiliated Hospital, Zhejiang University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-12-31
- Primary Completion
- 2015-12-31
- Completion
- 2015-12-31
Countries
- China
Study Locations
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