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Effects of Epidural Local Anesthetics on Propofol Induction

NCT02000973 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2014-05-16

Study results available
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Summary

The investigators designed a prospective, randomized, placebo-controlled study to determine whether thoracic epidural anesthesia(TEA) with different local anesthetics has different influences on the propofol dose during induction.

Conditions

  • General Anesthesia
  • Propofol Target-controlled Infusion
  • Thoracic Epidural Anesthesia

Interventions

DRUG

Lidocaine

General anesthesia combined with thoracic epidural 1% lidocaine

DRUG

Bupivacaine

General anesthesia combined with thoracic epidural 0.25% bupivacaine

DRUG

Ropivacaine

General anesthesia combined with thoracic epidural 0.3% ropivacaine

DRUG

Normal Saline

General anesthesia combined with thoracic epidural 0.9% normal saline

Sponsors & Collaborators

  • First Hospital of China Medical University

    lead OTHER

Principal Investigators

  • Jun Wang · Dept. of Anesthesiology, First Hospital of China Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2014-01-31
Completion
2014-03-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02000973 on ClinicalTrials.gov